Ectopic expression of the GABA sub(A) receptor alpha 6 subunit in hippocampal pyramidal neurons produces extrasynaptic receptors and an increased tonic inhibition

We generated transgenic (Thy1 alpha 6) mice in which the GABA sub(A) receptor alpha 6 subunit, whose expression is usually confined to granule cells of cerebellum and cochlear nuclei, is ectopically expressed under the control of the pan-neuronal Thy-1.2 promoter. Strong Thy1 alpha 6 subunit express...

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Veröffentlicht in:	Neuropharmacology 2002-09, Vol.43 (4), p.530-549
Hauptverfasser:	Wisden, W, Cope, D, Klausberger, T, Hauer, B, Sinkkonen, ST, Tretter, V, Lujan, R, Jones, A, Korpi, E R, Mody, I, Sieghart, W, Somogyi, P
Format:	Artikel
Sprache:	eng
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