Cloning and Functional Characterization of the Smooth Muscle Ether-a-go-go-related Gene K super(+) Channel. POTENTIAL ROLE OF A CONSERVED AMINO ACID SUBSTITUTION IN THE S4 REGION

The human ether-a-go-go-related gene (HERG) product forms the pore-forming subunit of the delayed rectifier K super(+) channel in the heart. Unlike the cardiac isoform, the erg K super(+) channels in native smooth muscle demonstrate gating properties consistent with a role in maintaining resting pot...

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Veröffentlicht in:	The Journal of biological chemistry 2003-01, Vol.278 (4), p.2503-2514
Hauptverfasser:	Shoeb, F, Malykhina, A P, Akbarali, H I
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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