Endotoxin Contamination in Recombinant Human Heat Shock Protein 70 (Hsp70) Preparation Is Responsible for the Induction of Tumor Necrosis Factor [alpha] Release by Murine Macrophages

Using commercially available recombinant human heat shock protein 70 (rhHsp70), recent studies have shown that rhHsp70 could induce the production of tumor necrosis factor [alpha] (TNF[alpha]) by macrophages and monocytes in a manner similar to lipopolysaccharide (LPS) e.g. via CD14 and Toll-like re...

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Veröffentlicht in:	The Journal of biological chemistry 2003-01, Vol.278 (1), p.174-179
Hauptverfasser:	Gao, B, Tsan, M
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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