Comparisons Between Cancer-Related and Noncancer-Related Lymphedema: An Overview of New Patients Referred to a Specialized Hospital-Based Center in Canada
Lymphedema is an irreversible inflammatory condition caused by accumulated lymph fluid and is associated with chronic swelling and increased risk of cellulitis. Our objectives were to: (1) describe the patient population referred to a Canadian lymphedema center and (2) compare lymphedema characteris...
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| Veröffentlicht in: | Lymphatic research and biology 2017-03, Vol.15 (1), p.64-69 |
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| creator | Shallwani, Shirin M Hodgson, Pamela Towers, Anna |
| description | Lymphedema is an irreversible inflammatory condition caused by accumulated lymph fluid and is associated with chronic swelling and increased risk of cellulitis. Our objectives were to: (1) describe the patient population referred to a Canadian lymphedema center and (2) compare lymphedema characteristics between patients with cancer and patients with noncancer diagnoses.
A retrospective cohort study was conducted of new patients referred for suspected lymphedema to a hospital-based center over a 2-year period. The mean age of the patients (n = 429) was 61.4 years; 85% were female and 81% had a history of cancer. Lymphedema characteristics were primary (7%) versus secondary (92%); upper body (51%) versus lower body (45%); unilateral (74%) versus bilateral (25%); and history of cellulitis (22%). Patients with noncancer diagnoses (n = 82) were more likely than patients with cancer diagnoses (n = 347) to have a history of cellulitis (44% vs. 17%), to have bilateral (61% vs. 16%) and lower limb (89% vs. 37%) lymphedema, and to experience a long delay between symptom onset and referral (14.0 vs. 3.5 years) (p |
| doi_str_mv | 10.1089/lrb.2016.0023 |
| format | Article |
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A retrospective cohort study was conducted of new patients referred for suspected lymphedema to a hospital-based center over a 2-year period. The mean age of the patients (n = 429) was 61.4 years; 85% were female and 81% had a history of cancer. Lymphedema characteristics were primary (7%) versus secondary (92%); upper body (51%) versus lower body (45%); unilateral (74%) versus bilateral (25%); and history of cellulitis (22%). Patients with noncancer diagnoses (n = 82) were more likely than patients with cancer diagnoses (n = 347) to have a history of cellulitis (44% vs. 17%), to have bilateral (61% vs. 16%) and lower limb (89% vs. 37%) lymphedema, and to experience a long delay between symptom onset and referral (14.0 vs. 3.5 years) (p < 0.001).
Most patients referred to our lymphedema center were female with a history of cancer. However, patients with noncancer diagnoses were more likely to have bilateral lower body lymphedema with an important history of cellulitis; this subgroup is at great risk of missed and delayed diagnoses in the medical setting and of experiencing long-term issues with mobility, recurrent hospitalizations, and poor quality of life.</description><identifier>ISSN: 1539-6851</identifier><identifier>EISSN: 1557-8585</identifier><identifier>DOI: 10.1089/lrb.2016.0023</identifier><identifier>PMID: 28135124</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Canada ; Cellulitis - complications ; Cellulitis - microbiology ; Female ; Humans ; Leg - pathology ; Leg - physiopathology ; Lymphedema - diagnosis ; Lymphedema - etiology ; Male ; Middle Aged ; Neoplasms - complications ; Retrospective Studies ; Severity of Illness Index ; Young Adult</subject><ispartof>Lymphatic research and biology, 2017-03, Vol.15 (1), p.64-69</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c293t-75ec5cbbe64b31bf08a50647e48fcc52952dde3533bf4be65aed951028d31c5b3</citedby><cites>FETCH-LOGICAL-c293t-75ec5cbbe64b31bf08a50647e48fcc52952dde3533bf4be65aed951028d31c5b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28135124$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shallwani, Shirin M</creatorcontrib><creatorcontrib>Hodgson, Pamela</creatorcontrib><creatorcontrib>Towers, Anna</creatorcontrib><title>Comparisons Between Cancer-Related and Noncancer-Related Lymphedema: An Overview of New Patients Referred to a Specialized Hospital-Based Center in Canada</title><title>Lymphatic research and biology</title><addtitle>Lymphat Res Biol</addtitle><description>Lymphedema is an irreversible inflammatory condition caused by accumulated lymph fluid and is associated with chronic swelling and increased risk of cellulitis. Our objectives were to: (1) describe the patient population referred to a Canadian lymphedema center and (2) compare lymphedema characteristics between patients with cancer and patients with noncancer diagnoses.
A retrospective cohort study was conducted of new patients referred for suspected lymphedema to a hospital-based center over a 2-year period. The mean age of the patients (n = 429) was 61.4 years; 85% were female and 81% had a history of cancer. Lymphedema characteristics were primary (7%) versus secondary (92%); upper body (51%) versus lower body (45%); unilateral (74%) versus bilateral (25%); and history of cellulitis (22%). Patients with noncancer diagnoses (n = 82) were more likely than patients with cancer diagnoses (n = 347) to have a history of cellulitis (44% vs. 17%), to have bilateral (61% vs. 16%) and lower limb (89% vs. 37%) lymphedema, and to experience a long delay between symptom onset and referral (14.0 vs. 3.5 years) (p < 0.001).
Most patients referred to our lymphedema center were female with a history of cancer. However, patients with noncancer diagnoses were more likely to have bilateral lower body lymphedema with an important history of cellulitis; this subgroup is at great risk of missed and delayed diagnoses in the medical setting and of experiencing long-term issues with mobility, recurrent hospitalizations, and poor quality of life.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Canada</subject><subject>Cellulitis - complications</subject><subject>Cellulitis - microbiology</subject><subject>Female</subject><subject>Humans</subject><subject>Leg - pathology</subject><subject>Leg - physiopathology</subject><subject>Lymphedema - diagnosis</subject><subject>Lymphedema - etiology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Neoplasms - complications</subject><subject>Retrospective Studies</subject><subject>Severity of Illness Index</subject><subject>Young Adult</subject><issn>1539-6851</issn><issn>1557-8585</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVkU9P3DAQxS1UxC60R67Ix16y-E-cdbgtUQtIqwXR9hxN7IkwSuJgZ0H0o_Bp8RaoxOnNjH7zRppHyDFnC850edqFZiEYLxaMCblH5lypZaaVVl92tSyzQis-I4cx3idCcCYOyExoLhUX-Zy8VL4fIbjoh0jPcXpCHGgFg8GQ3WIHE1oKg6UbP5jP0_VzP96hxR7O6Gqg148YHh0-Ud_STZIbmBwOU6S32GIIaWHyFOivEY2Dzv1Ng0sfRzdBl51DTG2VcAzU_bsPFr6S_Ra6iN_e9Yj8-fnjd3WZra8vrqrVOjOilFO2VGiUaRos8kbypmUaFCvyJea6NUaJUglrUSopmzZPlAK0pUp_0FZyoxp5RL6_-Y7BP2wxTnXvosGugwH9NtZcF1IIVi55QrM31AQfY8C2HoPrITzXnNW7OOoUR72Lo97FkfiTd-tt06P9T3_8X74C0I6HuA</recordid><startdate>201703</startdate><enddate>201703</enddate><creator>Shallwani, Shirin M</creator><creator>Hodgson, Pamela</creator><creator>Towers, Anna</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201703</creationdate><title>Comparisons Between Cancer-Related and Noncancer-Related Lymphedema: An Overview of New Patients Referred to a Specialized Hospital-Based Center in Canada</title><author>Shallwani, Shirin M ; Hodgson, Pamela ; Towers, Anna</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c293t-75ec5cbbe64b31bf08a50647e48fcc52952dde3533bf4be65aed951028d31c5b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Canada</topic><topic>Cellulitis - complications</topic><topic>Cellulitis - microbiology</topic><topic>Female</topic><topic>Humans</topic><topic>Leg - pathology</topic><topic>Leg - physiopathology</topic><topic>Lymphedema - diagnosis</topic><topic>Lymphedema - etiology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Neoplasms - complications</topic><topic>Retrospective Studies</topic><topic>Severity of Illness Index</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shallwani, Shirin M</creatorcontrib><creatorcontrib>Hodgson, Pamela</creatorcontrib><creatorcontrib>Towers, Anna</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Lymphatic research and biology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shallwani, Shirin M</au><au>Hodgson, Pamela</au><au>Towers, Anna</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparisons Between Cancer-Related and Noncancer-Related Lymphedema: An Overview of New Patients Referred to a Specialized Hospital-Based Center in Canada</atitle><jtitle>Lymphatic research and biology</jtitle><addtitle>Lymphat Res Biol</addtitle><date>2017-03</date><risdate>2017</risdate><volume>15</volume><issue>1</issue><spage>64</spage><epage>69</epage><pages>64-69</pages><issn>1539-6851</issn><eissn>1557-8585</eissn><abstract>Lymphedema is an irreversible inflammatory condition caused by accumulated lymph fluid and is associated with chronic swelling and increased risk of cellulitis. Our objectives were to: (1) describe the patient population referred to a Canadian lymphedema center and (2) compare lymphedema characteristics between patients with cancer and patients with noncancer diagnoses.
A retrospective cohort study was conducted of new patients referred for suspected lymphedema to a hospital-based center over a 2-year period. The mean age of the patients (n = 429) was 61.4 years; 85% were female and 81% had a history of cancer. Lymphedema characteristics were primary (7%) versus secondary (92%); upper body (51%) versus lower body (45%); unilateral (74%) versus bilateral (25%); and history of cellulitis (22%). Patients with noncancer diagnoses (n = 82) were more likely than patients with cancer diagnoses (n = 347) to have a history of cellulitis (44% vs. 17%), to have bilateral (61% vs. 16%) and lower limb (89% vs. 37%) lymphedema, and to experience a long delay between symptom onset and referral (14.0 vs. 3.5 years) (p < 0.001).
Most patients referred to our lymphedema center were female with a history of cancer. However, patients with noncancer diagnoses were more likely to have bilateral lower body lymphedema with an important history of cellulitis; this subgroup is at great risk of missed and delayed diagnoses in the medical setting and of experiencing long-term issues with mobility, recurrent hospitalizations, and poor quality of life.</abstract><cop>United States</cop><pmid>28135124</pmid><doi>10.1089/lrb.2016.0023</doi><tpages>6</tpages></addata></record> |
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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Aged Aged, 80 and over Canada Cellulitis - complications Cellulitis - microbiology Female Humans Leg - pathology Leg - physiopathology Lymphedema - diagnosis Lymphedema - etiology Male Middle Aged Neoplasms - complications Retrospective Studies Severity of Illness Index Young Adult |
| title | Comparisons Between Cancer-Related and Noncancer-Related Lymphedema: An Overview of New Patients Referred to a Specialized Hospital-Based Center in Canada |
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