Acid-sensing ion channel 1a is required for mGlu receptor dependent long-term depression in the hippocampus

[Display omitted] Acid-sensing ion channels (ASICs), members of the degenerin/epithelial Na+ channel superfamily, are widely distributed in the mammalian nervous system. ASIC1a is highly permeable to Ca2+ and are thought to be important in a variety of physiological processes, including synaptic pla...

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Veröffentlicht in:	Pharmacological research 2017-05, Vol.119, p.12-19
Hauptverfasser:	Mango, D., Braksator, E., Battaglia, G., Marcelli, S., Mercuri, N.B., Feligioni, M., Nicoletti, F., Bashir, Z.I., Nisticò, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acid Sensing Ion Channels - metabolism Action Potentials Animals ASIC Electrophysiology Hippocampus Hippocampus - physiology Long-Term Synaptic Depression LTD mGlu receptors Mice, Inbred C57BL Neuronal Plasticity Pyramidal Cells - physiology Receptors, Metabotropic Glutamate - metabolism
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