Raised faecal calprotectin is associated with subsequent symptomatic relapse, in children and adolescents with inflammatory bowel disease in clinical remission

SUMMARY Background Reliable data on inflammatory biomarkers for predicting relapse of paediatric inflammatory bowel disease (IBD) are lacking. Aim To investigate the predictive value of faecal calprotectin (FC) and CRP for symptomatic relapse in pediatric IBD in clinical remission. Methods In this c...

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Veröffentlicht in:	Alimentary pharmacology & therapeutics 2017-04, Vol.45 (7), p.951-960
Hauptverfasser:	Diederen, K., Hoekman, D. R., Leek, A., Wolters, V. M., Hummel, T. Z., de Meij, T. G., Koot, B. G. P., Tabbers, M. M., Benninga, M. A., Kindermann, A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adolescents Biomarkers - metabolism C-Reactive Protein - analysis Child Children Cohort Studies Colitis, Ulcerative - blood Colitis, Ulcerative - metabolism Colon Crohn Disease - blood Crohn Disease - metabolism Crohn's disease Crohns disease Cross-Sectional Studies Disease Progression Feces - chemistry Female Humans Inflammatory bowel disease Inflammatory bowel diseases Intestine Leukocyte L1 Antigen Complex - metabolism Male Males Pediatrics Recurrence Remission Ulcerative colitis
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Zusammenfassung:	SUMMARY Background Reliable data on inflammatory biomarkers for predicting relapse of paediatric inflammatory bowel disease (IBD) are lacking. Aim To investigate the predictive value of faecal calprotectin (FC) and CRP for symptomatic relapse in pediatric IBD in clinical remission. Methods In this cross‐sectional cohort study, patients
ISSN:	0269-2813 1365-2036
DOI:	10.1111/apt.13950