Post-transcriptional regulation of cyclin D1 expression during G2 phase

During continuous proliferation, cyclin D1 protein is induced to high levels in a Ras-dependent manner as cells progress from S phase to G2 phase. To understand the mechanism of the Ras-dependent cyclin D1 induction, cyclin D1 mRNA levels were determined by quantitative image analysis following fluo...

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Veröffentlicht in:	Oncogene 2002-10, Vol.21 (49), p.7545-7556
Hauptverfasser:	Guo, Yang, Stacey, Dennis W, Hitomi, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Amanitin Amanitins - pharmacology Animals Blotting, Northern Cell cycle Cyclin D1 Cyclin D1 - genetics D1 protein Fluorescence in situ hybridization Fluorescent Antibody Technique G2 Phase Gene expression Gene Expression Regulation - drug effects Gene regulation Growth factors Image processing In Situ Hybridization, Fluorescence Kinases Mice Microinjections Phase transitions Post-transcription Post-translation Proteins Ras protein RNA Processing, Post-Transcriptional S phase Transcription factors
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