Aortic arch reconstruction: deep and moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion
Objective: To compare the effects of moderate and deep hypothermic circulatory arrest (DHCA) with selective antegrade cerebral perfusion (SACP) during aortic arch surgery in adult patients and to offer the evidence for the detection of the temperature which provides best brain protection in the subj...
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| Veröffentlicht in: | Perfusion 2017-07, Vol.32 (5), p.389-393 |
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| creator | Wu, YanWen Xiao, LiQiong Yang, Ting Wang, Lei Chen, Xin |
| description | Objective:
To compare the effects of moderate and deep hypothermic circulatory arrest (DHCA) with selective antegrade cerebral perfusion (SACP) during aortic arch surgery in adult patients and to offer the evidence for the detection of the temperature which provides best brain protection in the subjects who accept aortic arch reconstruction surgery.
Methods:
A total of 109 patients undergoing surgery of the aortic arch were divided into the moderate hypothermic circulatory arrest group (Group I) and the deep hypothermic circulatory arrest group (Group II). We recorded the data of the patients and their cardiopulmonary bypass (CPB) time, aortic clamping time, SACP time and postoperative anesthetized recovery time, tracheal intubation time, time in the intensive care unit (ICU) and postoperative neurologic dysfunction.
Results:
Patient characteristics were similar in the two groups. There were four patients who died in Group II and 1 patient in Group I. There were no significant differences in aortic clamping time of each group (111.4±58.4 vs. 115.9±16.2) min; SACP time (27.4±5.9 vs. 23.5±6.1) min of the moderate hypothermic circulatory arrest group and the deep hypothermic circulatory arrest group; there were significant differences in cardiopulmonary bypass time (207.4±20.9 vs. 263.8±22.6) min, postoperative anesthetized recovery time (19.0±11.1 vs. 36.8±25.3) hours, extubation time (46.4±15.1 vs. 64.4±6.0) hours; length of stay in the intensive care unit (ICU) (4.7±1.7 vs. 8±2.3) days and postoperative neurologic dysfunction in the two groups.
Conclusion:
Compared to deep hypothermic circulatory arrest, moderate hypothermic circulatory arrest can provide better brain protection and achieve good clinical results. |
| doi_str_mv | 10.1177/0267659116688423 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1862937331</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_0267659116688423</sage_id><sourcerecordid>1906687407</sourcerecordid><originalsourceid>FETCH-LOGICAL-c365t-1028910ea724eafaad88c5431d59b31c2dd01c50128f09930113afb6b4e82afb3</originalsourceid><addsrcrecordid>eNp1kUGL1TAURoMozpvRvSsJuHFTzU3SJnU3DOoIA24U3JU0uZ3XoW3qTaq-f28ebxQZcJXAPefLJR9jL0C8ATDmrZCNaeoWoGms1VI9YjvQxlQA8O0x2x3H1XF-xs5TuhNCaK3VU3YmLShZW7Njvy4j5dFzR37PCX1cUqbN5zEu73hAXLlbAp9jQHIZ-f6wxrxHmoviR_Lb5HKkQ9EJU-Y_x7znCScsAT-wqBlvyQXkHgl7chNfkYYtlfRn7MngpoTP788L9vXD-y9X19XN54-fri5vKq-aOlcgpG1BoDNSoxucC9b6WisIddsr8DIEAb4WIO0g2lYJAOWGvuk1Wlku6oK9PuWuFL9vZcluHpPHaXILxi11YBvZKqMUFPTVA_QubrSU7TpoRflio4UplDhRnmJKhEO30jg7OnQgumMr3cNWivLyPnjrZwx_hT81FKA6Acnd4j-v_i_wNzKuljE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1906687407</pqid></control><display><type>article</type><title>Aortic arch reconstruction: deep and moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion</title><source>SAGE Complete A-Z List</source><source>MEDLINE</source><creator>Wu, YanWen ; Xiao, LiQiong ; Yang, Ting ; Wang, Lei ; Chen, Xin</creator><creatorcontrib>Wu, YanWen ; Xiao, LiQiong ; Yang, Ting ; Wang, Lei ; Chen, Xin</creatorcontrib><description>Objective:
To compare the effects of moderate and deep hypothermic circulatory arrest (DHCA) with selective antegrade cerebral perfusion (SACP) during aortic arch surgery in adult patients and to offer the evidence for the detection of the temperature which provides best brain protection in the subjects who accept aortic arch reconstruction surgery.
Methods:
A total of 109 patients undergoing surgery of the aortic arch were divided into the moderate hypothermic circulatory arrest group (Group I) and the deep hypothermic circulatory arrest group (Group II). We recorded the data of the patients and their cardiopulmonary bypass (CPB) time, aortic clamping time, SACP time and postoperative anesthetized recovery time, tracheal intubation time, time in the intensive care unit (ICU) and postoperative neurologic dysfunction.
Results:
Patient characteristics were similar in the two groups. There were four patients who died in Group II and 1 patient in Group I. There were no significant differences in aortic clamping time of each group (111.4±58.4 vs. 115.9±16.2) min; SACP time (27.4±5.9 vs. 23.5±6.1) min of the moderate hypothermic circulatory arrest group and the deep hypothermic circulatory arrest group; there were significant differences in cardiopulmonary bypass time (207.4±20.9 vs. 263.8±22.6) min, postoperative anesthetized recovery time (19.0±11.1 vs. 36.8±25.3) hours, extubation time (46.4±15.1 vs. 64.4±6.0) hours; length of stay in the intensive care unit (ICU) (4.7±1.7 vs. 8±2.3) days and postoperative neurologic dysfunction in the two groups.
Conclusion:
Compared to deep hypothermic circulatory arrest, moderate hypothermic circulatory arrest can provide better brain protection and achieve good clinical results.</description><identifier>ISSN: 0267-6591</identifier><identifier>EISSN: 1477-111X</identifier><identifier>DOI: 10.1177/0267659116688423</identifier><identifier>PMID: 28132587</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Adult ; Aorta, Thoracic ; Aortic arch ; Brain ; Bypasses ; Circulatory Arrest, Deep Hypothermia Induced - adverse effects ; Circulatory Arrest, Deep Hypothermia Induced - methods ; Circulatory system ; Clamping ; Critical Care ; Extubation ; Female ; Heart surgery ; Humans ; Intensive care ; Intubation ; Male ; Middle Aged ; Patients ; Perfusion ; Perfusion - adverse effects ; Perfusion - methods ; Reconstruction ; Recovery time ; Surgery ; Temperature effects ; Time Factors</subject><ispartof>Perfusion, 2017-07, Vol.32 (5), p.389-393</ispartof><rights>The Author(s) 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c365t-1028910ea724eafaad88c5431d59b31c2dd01c50128f09930113afb6b4e82afb3</citedby><cites>FETCH-LOGICAL-c365t-1028910ea724eafaad88c5431d59b31c2dd01c50128f09930113afb6b4e82afb3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/0267659116688423$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/0267659116688423$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21800,27903,27904,43600,43601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28132587$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wu, YanWen</creatorcontrib><creatorcontrib>Xiao, LiQiong</creatorcontrib><creatorcontrib>Yang, Ting</creatorcontrib><creatorcontrib>Wang, Lei</creatorcontrib><creatorcontrib>Chen, Xin</creatorcontrib><title>Aortic arch reconstruction: deep and moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion</title><title>Perfusion</title><addtitle>Perfusion</addtitle><description>Objective:
To compare the effects of moderate and deep hypothermic circulatory arrest (DHCA) with selective antegrade cerebral perfusion (SACP) during aortic arch surgery in adult patients and to offer the evidence for the detection of the temperature which provides best brain protection in the subjects who accept aortic arch reconstruction surgery.
Methods:
A total of 109 patients undergoing surgery of the aortic arch were divided into the moderate hypothermic circulatory arrest group (Group I) and the deep hypothermic circulatory arrest group (Group II). We recorded the data of the patients and their cardiopulmonary bypass (CPB) time, aortic clamping time, SACP time and postoperative anesthetized recovery time, tracheal intubation time, time in the intensive care unit (ICU) and postoperative neurologic dysfunction.
Results:
Patient characteristics were similar in the two groups. There were four patients who died in Group II and 1 patient in Group I. There were no significant differences in aortic clamping time of each group (111.4±58.4 vs. 115.9±16.2) min; SACP time (27.4±5.9 vs. 23.5±6.1) min of the moderate hypothermic circulatory arrest group and the deep hypothermic circulatory arrest group; there were significant differences in cardiopulmonary bypass time (207.4±20.9 vs. 263.8±22.6) min, postoperative anesthetized recovery time (19.0±11.1 vs. 36.8±25.3) hours, extubation time (46.4±15.1 vs. 64.4±6.0) hours; length of stay in the intensive care unit (ICU) (4.7±1.7 vs. 8±2.3) days and postoperative neurologic dysfunction in the two groups.
Conclusion:
Compared to deep hypothermic circulatory arrest, moderate hypothermic circulatory arrest can provide better brain protection and achieve good clinical results.</description><subject>Adult</subject><subject>Aorta, Thoracic</subject><subject>Aortic arch</subject><subject>Brain</subject><subject>Bypasses</subject><subject>Circulatory Arrest, Deep Hypothermia Induced - adverse effects</subject><subject>Circulatory Arrest, Deep Hypothermia Induced - methods</subject><subject>Circulatory system</subject><subject>Clamping</subject><subject>Critical Care</subject><subject>Extubation</subject><subject>Female</subject><subject>Heart surgery</subject><subject>Humans</subject><subject>Intensive care</subject><subject>Intubation</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Patients</subject><subject>Perfusion</subject><subject>Perfusion - adverse effects</subject><subject>Perfusion - methods</subject><subject>Reconstruction</subject><subject>Recovery time</subject><subject>Surgery</subject><subject>Temperature effects</subject><subject>Time Factors</subject><issn>0267-6591</issn><issn>1477-111X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kUGL1TAURoMozpvRvSsJuHFTzU3SJnU3DOoIA24U3JU0uZ3XoW3qTaq-f28ebxQZcJXAPefLJR9jL0C8ATDmrZCNaeoWoGms1VI9YjvQxlQA8O0x2x3H1XF-xs5TuhNCaK3VU3YmLShZW7Njvy4j5dFzR37PCX1cUqbN5zEu73hAXLlbAp9jQHIZ-f6wxrxHmoviR_Lb5HKkQ9EJU-Y_x7znCScsAT-wqBlvyQXkHgl7chNfkYYtlfRn7MngpoTP788L9vXD-y9X19XN54-fri5vKq-aOlcgpG1BoDNSoxucC9b6WisIddsr8DIEAb4WIO0g2lYJAOWGvuk1Wlku6oK9PuWuFL9vZcluHpPHaXILxi11YBvZKqMUFPTVA_QubrSU7TpoRflio4UplDhRnmJKhEO30jg7OnQgumMr3cNWivLyPnjrZwx_hT81FKA6Acnd4j-v_i_wNzKuljE</recordid><startdate>201707</startdate><enddate>201707</enddate><creator>Wu, YanWen</creator><creator>Xiao, LiQiong</creator><creator>Yang, Ting</creator><creator>Wang, Lei</creator><creator>Chen, Xin</creator><general>SAGE Publications</general><general>Sage Publications Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7U7</scope><scope>C1K</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>201707</creationdate><title>Aortic arch reconstruction: deep and moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion</title><author>Wu, YanWen ; Xiao, LiQiong ; Yang, Ting ; Wang, Lei ; Chen, Xin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c365t-1028910ea724eafaad88c5431d59b31c2dd01c50128f09930113afb6b4e82afb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Aorta, Thoracic</topic><topic>Aortic arch</topic><topic>Brain</topic><topic>Bypasses</topic><topic>Circulatory Arrest, Deep Hypothermia Induced - adverse effects</topic><topic>Circulatory Arrest, Deep Hypothermia Induced - methods</topic><topic>Circulatory system</topic><topic>Clamping</topic><topic>Critical Care</topic><topic>Extubation</topic><topic>Female</topic><topic>Heart surgery</topic><topic>Humans</topic><topic>Intensive care</topic><topic>Intubation</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Patients</topic><topic>Perfusion</topic><topic>Perfusion - adverse effects</topic><topic>Perfusion - methods</topic><topic>Reconstruction</topic><topic>Recovery time</topic><topic>Surgery</topic><topic>Temperature effects</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wu, YanWen</creatorcontrib><creatorcontrib>Xiao, LiQiong</creatorcontrib><creatorcontrib>Yang, Ting</creatorcontrib><creatorcontrib>Wang, Lei</creatorcontrib><creatorcontrib>Chen, Xin</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Perfusion</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wu, YanWen</au><au>Xiao, LiQiong</au><au>Yang, Ting</au><au>Wang, Lei</au><au>Chen, Xin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Aortic arch reconstruction: deep and moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion</atitle><jtitle>Perfusion</jtitle><addtitle>Perfusion</addtitle><date>2017-07</date><risdate>2017</risdate><volume>32</volume><issue>5</issue><spage>389</spage><epage>393</epage><pages>389-393</pages><issn>0267-6591</issn><eissn>1477-111X</eissn><abstract>Objective:
To compare the effects of moderate and deep hypothermic circulatory arrest (DHCA) with selective antegrade cerebral perfusion (SACP) during aortic arch surgery in adult patients and to offer the evidence for the detection of the temperature which provides best brain protection in the subjects who accept aortic arch reconstruction surgery.
Methods:
A total of 109 patients undergoing surgery of the aortic arch were divided into the moderate hypothermic circulatory arrest group (Group I) and the deep hypothermic circulatory arrest group (Group II). We recorded the data of the patients and their cardiopulmonary bypass (CPB) time, aortic clamping time, SACP time and postoperative anesthetized recovery time, tracheal intubation time, time in the intensive care unit (ICU) and postoperative neurologic dysfunction.
Results:
Patient characteristics were similar in the two groups. There were four patients who died in Group II and 1 patient in Group I. There were no significant differences in aortic clamping time of each group (111.4±58.4 vs. 115.9±16.2) min; SACP time (27.4±5.9 vs. 23.5±6.1) min of the moderate hypothermic circulatory arrest group and the deep hypothermic circulatory arrest group; there were significant differences in cardiopulmonary bypass time (207.4±20.9 vs. 263.8±22.6) min, postoperative anesthetized recovery time (19.0±11.1 vs. 36.8±25.3) hours, extubation time (46.4±15.1 vs. 64.4±6.0) hours; length of stay in the intensive care unit (ICU) (4.7±1.7 vs. 8±2.3) days and postoperative neurologic dysfunction in the two groups.
Conclusion:
Compared to deep hypothermic circulatory arrest, moderate hypothermic circulatory arrest can provide better brain protection and achieve good clinical results.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>28132587</pmid><doi>10.1177/0267659116688423</doi><tpages>5</tpages></addata></record> |
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| ispartof | Perfusion, 2017-07, Vol.32 (5), p.389-393 |
| issn | 0267-6591 1477-111X |
| language | eng |
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| source | SAGE Complete A-Z List; MEDLINE |
| subjects | Adult Aorta, Thoracic Aortic arch Brain Bypasses Circulatory Arrest, Deep Hypothermia Induced - adverse effects Circulatory Arrest, Deep Hypothermia Induced - methods Circulatory system Clamping Critical Care Extubation Female Heart surgery Humans Intensive care Intubation Male Middle Aged Patients Perfusion Perfusion - adverse effects Perfusion - methods Reconstruction Recovery time Surgery Temperature effects Time Factors |
| title | Aortic arch reconstruction: deep and moderate hypothermic circulatory arrest with selective antegrade cerebral perfusion |
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