Application of Biocatalysis to on‐DNA Carbohydrate Library Synthesis

DNA‐encoded libraries are increasingly used for the discovery of bioactive lead compounds in high‐throughput screening programs against specific biological targets. Although a number of libraries are now available, they cover limited chemical space due to bias in ease of synthesis and the lack of ch...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2017-05, Vol.18 (9), p.858-863
Hauptverfasser:	Thomas, Baptiste, Lu, Xiaojie, Birmingham, William R., Huang, Kun, Both, Peter, Reyes Martinez, Juana Elizabeth, Young, Robert J., Davie, Christopher P., Flitsch, Sabine L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aqueous environments Biocatalysis Biocompatibility Biomolecules biotransformation carbohydrate Carbohydrates Carbohydrates - chemistry Catalysis Chemical reactions Chemical synthesis Deoxyribonucleic acid DNA DNA - chemistry DNA - metabolism DNA biosynthesis DNA-encoded libraries glycoconjugate Glycoconjugates - chemistry Glycoconjugates - metabolism Glycosylation High-throughput screening Lead compounds Neuraminidase - metabolism Organic chemistry Oxidation Oxidation-Reduction Photobacterium - enzymology Sialyltransferases - metabolism Small Molecule Libraries - chemistry Stereochemistry Trypanosoma cruzi - enzymology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!