Alzheimer's disease: Innate immunity gone awry?

Abstract Inflammation is an immune activity designed to protect the host from pathogens and noxious agents. In its low-intensity form, presence of an inflammatory process must be inferred from appropriate biomarkers. Occult neuroinflammation is not just secondary to Alzheimer's disease (AD) but...

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Veröffentlicht in:	Metabolism, clinical and experimental clinical and experimental, 2017-04, Vol.69, p.S41-S49
1. Verfasser:	VanItallie, Theodore B
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylation Adaptive Immunity Aged Aged, 80 and over Alzheimer Disease - immunology Alzheimer Disease - metabolism Alzheimer Disease - physiopathology Alzheimer Disease - prevention & control Animals Astrocytes - immunology Astrocytes - metabolism Blood-Brain Barrier - immunology Blood-Brain Barrier - metabolism Blood-Brain Barrier - physiopathology Blood–brain barrier Complement activation Disease Progression Endocrinology & Metabolism Exercise Hippocampus - immunology Hippocampus - metabolism Hippocampus - physiopathology Histones - metabolism Humans Immunity, Innate Inflammasomes - immunology Inflammasomes - metabolism Microglia Microglia - immunology Microglia - metabolism Mitochondria - immunology Mitochondria - metabolism Neuroimmunomodulation Neuroinflammation Protein Processing, Post-Translational Synapses - immunology Synapses - metabolism β-Hydroxybutyrate
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