Suppression of 5′ splice-sites through multiple exonic motifs by hnRNP L

Selection of 5′ splice-sites (5′SS) in alternative splicing plays an important role in gene regulation. Although regulatory mechanisms of heterogeneous nuclear ribonucleoprotein L (hnRNP L), a well-known splicing regulatory protein, have been studied in a substantial level, its role in 5′SS selectio...

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Veröffentlicht in:Biochimica et biophysica acta. Gene regulatory mechanisms 2017-03, Vol.1860 (3), p.363-373
Hauptverfasser: Loh, Tiing Jen, Choi, Namjeong, Moon, Heegyum, Jang, Ha Na, Liu, Yongchao, Zhou, Jianhua, Zheng, Xuexiu, Shen, Haihong
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Sprache:eng
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