Cysteamine pre-treatment reduces pentylenetetrazol-induced plasticity and epileptiform discharge in the CA1 region of rat hippocampal slices

The effects of prior treatment of cysteamine, a somatostatin inhibitor, on pentylenetetrazol (PTZ) induced epileptic and plastic changes in CA1 excitability were examined. Population spikes were evoked by activation of Schaffer collaterals with a range of stimulation intensities. Changes in the popu...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research 2002-11, Vol.955 (1), p.98-103
Hauptverfasser:	Rostampour, Mohammad, Fathollahi, Yaghoub, Semnanian, Saeed, Hajizadeh, Sohrab, Mirnajafizadeh, Javad, Shafizadeh, Mahshied
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials - drug effects Action Potentials - physiology Animals Biological and medical sciences Cysteamine Cysteamine - pharmacology Cysteamine - therapeutic use Epilepsy - chemically induced Epilepsy - drug therapy Epilepsy - physiopathology Excitatory Postsynaptic Potentials - drug effects Excitatory Postsynaptic Potentials - physiology Field potential Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy Hippocampus Hippocampus - drug effects Hippocampus - physiology In vitro In Vitro Techniques Male Medical sciences Nervous system (semeiology, syndromes) Neurology Neuronal Plasticity - drug effects Neuronal Plasticity - physiology Pentylenetetrazol Pentylenetetrazole - adverse effects Rats Somatostatin Synaptic plasticity
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!