Surgical Technique for Decompression of Severe Thoracic Myelopathy due to Tuberous Ossification of Ligamentum Flavum

Retrospective review. To describe a safe surgical procedure, en bloc resection of the posterior wall of the thoracic canal, for the decompression of severe thoracic myelopathy caused by tuberous ossification of the ligamentum flavum (OLF). OLF has been widely recognized as a cause of thoracic myelop...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Clinical spine surgery 2017-02, Vol.30 (1), p.E7-E12
Hauptverfasser: Wang, Ting, Yin, Chuqiang, Wang, Dechun, Li, Shuzhong, Chen, Xiaoliang
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page E12
container_issue 1
container_start_page E7
container_title Clinical spine surgery
container_volume 30
creator Wang, Ting
Yin, Chuqiang
Wang, Dechun
Li, Shuzhong
Chen, Xiaoliang
description Retrospective review. To describe a safe surgical procedure, en bloc resection of the posterior wall of the thoracic canal, for the decompression of severe thoracic myelopathy caused by tuberous ossification of the ligamentum flavum (OLF). OLF has been widely recognized as a cause of thoracic myelopathy in East Asia. Surgical decompression of thoracic myelopathy caused by OLF is technically demanding. Although several surgical decompression procedures have been described, acute neurological deterioration is common. Eighteen patients with severe thoracic myelopathy caused by tuberous OLF underwent posterior decompression via segmental en bloc resection of the posterior wall of the thoracic canal. The ossified ligamentum flavum, laminae, and partial facet joints of each segment were resected en bloc. Ossified dura mater was removed if present. Posterior fixation with pedicle screws was followed by lateral bone graft fusion. The mean preoperative modified Japanese Orthopaedic Association score (total score, 11) was 4.1 (range, 2-5). Postoperatively, no neurological deterioration occurred, and all patients improved clinically. With an average follow-up of 31.2 months (range, 24-42 mo), the average modified Japanese Orthopaedic Association score was 7.8 (range, 6-10), representing a 2- to 5-point improvement. The average improvement rate was 55.2% (range, 33.3%-83.3%). Most patients were functionally independent at the last follow-up. Forty ossified segments were resected. The average time required for the resection of 1 segment was 77 minutes. Intraoperatively, dural ossification was noted in 11 patients. Complete resection was performed in all patients. Cerebrospinal fluid leakage occurred in 5 patients. Segmental en bloc resection of the posterior wall of the thoracic canal is a safe and effective alternative for OLF-related severe thoracic myelopathy.
doi_str_mv 10.1097/BSD.0000000000000213
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1861586921</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1861586921</sourcerecordid><originalsourceid>FETCH-LOGICAL-c443t-3de19e4750d482312936842311df473051c5379d7d96a5eeb83b4938342f385f3</originalsourceid><addsrcrecordid>eNpdkE1PwkAQQDdGIwT5B8bs0Qu429m226OCqAmGA_XcbLdTqGm7uNuS8O9dAxLjXGYO8-bjEXLL2ZSzJH54Ws-n7G8EHC7IMADJJown4vJcy2hAxs59-h4eQcwhvCaDQHIWBxANSbfu7abSqqYp6m1bffVIS2PpHLVpdhadq0xLTUnXuEeLNN0aq3Sl6fsBa7NT3fZAC890hqZ9jtb0jq48VPqZ3QldVhvVYNv1DV3Uat83N-SqVLXD8SmPyMfiOZ29Tparl7fZ43KihYBuAgXyBEUcskLIAHiQQCSFL3hRihhYyHUIcVLERRKpEDGXkIsEJIigBBmWMCL3x7k7a_xjrsuaymmsa9WiPzTzcngoo8TLGxFxbNXWOGexzHa2apQ9ZJxlP8ozrzz7r9xjd6cNfd5gcYZ-BcM3C7N7sQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1861586921</pqid></control><display><type>article</type><title>Surgical Technique for Decompression of Severe Thoracic Myelopathy due to Tuberous Ossification of Ligamentum Flavum</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Wang, Ting ; Yin, Chuqiang ; Wang, Dechun ; Li, Shuzhong ; Chen, Xiaoliang</creator><creatorcontrib>Wang, Ting ; Yin, Chuqiang ; Wang, Dechun ; Li, Shuzhong ; Chen, Xiaoliang</creatorcontrib><description>Retrospective review. To describe a safe surgical procedure, en bloc resection of the posterior wall of the thoracic canal, for the decompression of severe thoracic myelopathy caused by tuberous ossification of the ligamentum flavum (OLF). OLF has been widely recognized as a cause of thoracic myelopathy in East Asia. Surgical decompression of thoracic myelopathy caused by OLF is technically demanding. Although several surgical decompression procedures have been described, acute neurological deterioration is common. Eighteen patients with severe thoracic myelopathy caused by tuberous OLF underwent posterior decompression via segmental en bloc resection of the posterior wall of the thoracic canal. The ossified ligamentum flavum, laminae, and partial facet joints of each segment were resected en bloc. Ossified dura mater was removed if present. Posterior fixation with pedicle screws was followed by lateral bone graft fusion. The mean preoperative modified Japanese Orthopaedic Association score (total score, 11) was 4.1 (range, 2-5). Postoperatively, no neurological deterioration occurred, and all patients improved clinically. With an average follow-up of 31.2 months (range, 24-42 mo), the average modified Japanese Orthopaedic Association score was 7.8 (range, 6-10), representing a 2- to 5-point improvement. The average improvement rate was 55.2% (range, 33.3%-83.3%). Most patients were functionally independent at the last follow-up. Forty ossified segments were resected. The average time required for the resection of 1 segment was 77 minutes. Intraoperatively, dural ossification was noted in 11 patients. Complete resection was performed in all patients. Cerebrospinal fluid leakage occurred in 5 patients. Segmental en bloc resection of the posterior wall of the thoracic canal is a safe and effective alternative for OLF-related severe thoracic myelopathy.</description><identifier>ISSN: 2380-0186</identifier><identifier>EISSN: 2380-0194</identifier><identifier>DOI: 10.1097/BSD.0000000000000213</identifier><identifier>PMID: 28107236</identifier><language>eng</language><publisher>United States</publisher><subject>Aged ; Decompression, Surgical - adverse effects ; Decompression, Surgical - methods ; Female ; Humans ; Ligamentum Flavum - pathology ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Nervous System Diseases - etiology ; Ossification, Heterotopic - complications ; Ossification, Heterotopic - pathology ; Outcome Assessment (Health Care) ; Pedicle Screws ; Retrospective Studies ; Spinal Cord Diseases - etiology ; Spinal Cord Diseases - surgery ; Thoracic Vertebrae - surgery ; Tomography Scanners, X-Ray Computed ; Treatment Outcome</subject><ispartof>Clinical spine surgery, 2017-02, Vol.30 (1), p.E7-E12</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c443t-3de19e4750d482312936842311df473051c5379d7d96a5eeb83b4938342f385f3</citedby><cites>FETCH-LOGICAL-c443t-3de19e4750d482312936842311df473051c5379d7d96a5eeb83b4938342f385f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28107236$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Ting</creatorcontrib><creatorcontrib>Yin, Chuqiang</creatorcontrib><creatorcontrib>Wang, Dechun</creatorcontrib><creatorcontrib>Li, Shuzhong</creatorcontrib><creatorcontrib>Chen, Xiaoliang</creatorcontrib><title>Surgical Technique for Decompression of Severe Thoracic Myelopathy due to Tuberous Ossification of Ligamentum Flavum</title><title>Clinical spine surgery</title><addtitle>Clin Spine Surg</addtitle><description>Retrospective review. To describe a safe surgical procedure, en bloc resection of the posterior wall of the thoracic canal, for the decompression of severe thoracic myelopathy caused by tuberous ossification of the ligamentum flavum (OLF). OLF has been widely recognized as a cause of thoracic myelopathy in East Asia. Surgical decompression of thoracic myelopathy caused by OLF is technically demanding. Although several surgical decompression procedures have been described, acute neurological deterioration is common. Eighteen patients with severe thoracic myelopathy caused by tuberous OLF underwent posterior decompression via segmental en bloc resection of the posterior wall of the thoracic canal. The ossified ligamentum flavum, laminae, and partial facet joints of each segment were resected en bloc. Ossified dura mater was removed if present. Posterior fixation with pedicle screws was followed by lateral bone graft fusion. The mean preoperative modified Japanese Orthopaedic Association score (total score, 11) was 4.1 (range, 2-5). Postoperatively, no neurological deterioration occurred, and all patients improved clinically. With an average follow-up of 31.2 months (range, 24-42 mo), the average modified Japanese Orthopaedic Association score was 7.8 (range, 6-10), representing a 2- to 5-point improvement. The average improvement rate was 55.2% (range, 33.3%-83.3%). Most patients were functionally independent at the last follow-up. Forty ossified segments were resected. The average time required for the resection of 1 segment was 77 minutes. Intraoperatively, dural ossification was noted in 11 patients. Complete resection was performed in all patients. Cerebrospinal fluid leakage occurred in 5 patients. Segmental en bloc resection of the posterior wall of the thoracic canal is a safe and effective alternative for OLF-related severe thoracic myelopathy.</description><subject>Aged</subject><subject>Decompression, Surgical - adverse effects</subject><subject>Decompression, Surgical - methods</subject><subject>Female</subject><subject>Humans</subject><subject>Ligamentum Flavum - pathology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Nervous System Diseases - etiology</subject><subject>Ossification, Heterotopic - complications</subject><subject>Ossification, Heterotopic - pathology</subject><subject>Outcome Assessment (Health Care)</subject><subject>Pedicle Screws</subject><subject>Retrospective Studies</subject><subject>Spinal Cord Diseases - etiology</subject><subject>Spinal Cord Diseases - surgery</subject><subject>Thoracic Vertebrae - surgery</subject><subject>Tomography Scanners, X-Ray Computed</subject><subject>Treatment Outcome</subject><issn>2380-0186</issn><issn>2380-0194</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkE1PwkAQQDdGIwT5B8bs0Qu429m226OCqAmGA_XcbLdTqGm7uNuS8O9dAxLjXGYO8-bjEXLL2ZSzJH54Ws-n7G8EHC7IMADJJown4vJcy2hAxs59-h4eQcwhvCaDQHIWBxANSbfu7abSqqYp6m1bffVIS2PpHLVpdhadq0xLTUnXuEeLNN0aq3Sl6fsBa7NT3fZAC890hqZ9jtb0jq48VPqZ3QldVhvVYNv1DV3Uat83N-SqVLXD8SmPyMfiOZ29Tparl7fZ43KihYBuAgXyBEUcskLIAHiQQCSFL3hRihhYyHUIcVLERRKpEDGXkIsEJIigBBmWMCL3x7k7a_xjrsuaymmsa9WiPzTzcngoo8TLGxFxbNXWOGexzHa2apQ9ZJxlP8ozrzz7r9xjd6cNfd5gcYZ-BcM3C7N7sQ</recordid><startdate>20170201</startdate><enddate>20170201</enddate><creator>Wang, Ting</creator><creator>Yin, Chuqiang</creator><creator>Wang, Dechun</creator><creator>Li, Shuzhong</creator><creator>Chen, Xiaoliang</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170201</creationdate><title>Surgical Technique for Decompression of Severe Thoracic Myelopathy due to Tuberous Ossification of Ligamentum Flavum</title><author>Wang, Ting ; Yin, Chuqiang ; Wang, Dechun ; Li, Shuzhong ; Chen, Xiaoliang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c443t-3de19e4750d482312936842311df473051c5379d7d96a5eeb83b4938342f385f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Aged</topic><topic>Decompression, Surgical - adverse effects</topic><topic>Decompression, Surgical - methods</topic><topic>Female</topic><topic>Humans</topic><topic>Ligamentum Flavum - pathology</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Nervous System Diseases - etiology</topic><topic>Ossification, Heterotopic - complications</topic><topic>Ossification, Heterotopic - pathology</topic><topic>Outcome Assessment (Health Care)</topic><topic>Pedicle Screws</topic><topic>Retrospective Studies</topic><topic>Spinal Cord Diseases - etiology</topic><topic>Spinal Cord Diseases - surgery</topic><topic>Thoracic Vertebrae - surgery</topic><topic>Tomography Scanners, X-Ray Computed</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Ting</creatorcontrib><creatorcontrib>Yin, Chuqiang</creatorcontrib><creatorcontrib>Wang, Dechun</creatorcontrib><creatorcontrib>Li, Shuzhong</creatorcontrib><creatorcontrib>Chen, Xiaoliang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical spine surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Ting</au><au>Yin, Chuqiang</au><au>Wang, Dechun</au><au>Li, Shuzhong</au><au>Chen, Xiaoliang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Surgical Technique for Decompression of Severe Thoracic Myelopathy due to Tuberous Ossification of Ligamentum Flavum</atitle><jtitle>Clinical spine surgery</jtitle><addtitle>Clin Spine Surg</addtitle><date>2017-02-01</date><risdate>2017</risdate><volume>30</volume><issue>1</issue><spage>E7</spage><epage>E12</epage><pages>E7-E12</pages><issn>2380-0186</issn><eissn>2380-0194</eissn><abstract>Retrospective review. To describe a safe surgical procedure, en bloc resection of the posterior wall of the thoracic canal, for the decompression of severe thoracic myelopathy caused by tuberous ossification of the ligamentum flavum (OLF). OLF has been widely recognized as a cause of thoracic myelopathy in East Asia. Surgical decompression of thoracic myelopathy caused by OLF is technically demanding. Although several surgical decompression procedures have been described, acute neurological deterioration is common. Eighteen patients with severe thoracic myelopathy caused by tuberous OLF underwent posterior decompression via segmental en bloc resection of the posterior wall of the thoracic canal. The ossified ligamentum flavum, laminae, and partial facet joints of each segment were resected en bloc. Ossified dura mater was removed if present. Posterior fixation with pedicle screws was followed by lateral bone graft fusion. The mean preoperative modified Japanese Orthopaedic Association score (total score, 11) was 4.1 (range, 2-5). Postoperatively, no neurological deterioration occurred, and all patients improved clinically. With an average follow-up of 31.2 months (range, 24-42 mo), the average modified Japanese Orthopaedic Association score was 7.8 (range, 6-10), representing a 2- to 5-point improvement. The average improvement rate was 55.2% (range, 33.3%-83.3%). Most patients were functionally independent at the last follow-up. Forty ossified segments were resected. The average time required for the resection of 1 segment was 77 minutes. Intraoperatively, dural ossification was noted in 11 patients. Complete resection was performed in all patients. Cerebrospinal fluid leakage occurred in 5 patients. Segmental en bloc resection of the posterior wall of the thoracic canal is a safe and effective alternative for OLF-related severe thoracic myelopathy.</abstract><cop>United States</cop><pmid>28107236</pmid><doi>10.1097/BSD.0000000000000213</doi></addata></record>
fulltext fulltext
identifier ISSN: 2380-0186
ispartof Clinical spine surgery, 2017-02, Vol.30 (1), p.E7-E12
issn 2380-0186
2380-0194
language eng
recordid cdi_proquest_miscellaneous_1861586921
source MEDLINE; Journals@Ovid Complete
subjects Aged
Decompression, Surgical - adverse effects
Decompression, Surgical - methods
Female
Humans
Ligamentum Flavum - pathology
Magnetic Resonance Imaging
Male
Middle Aged
Nervous System Diseases - etiology
Ossification, Heterotopic - complications
Ossification, Heterotopic - pathology
Outcome Assessment (Health Care)
Pedicle Screws
Retrospective Studies
Spinal Cord Diseases - etiology
Spinal Cord Diseases - surgery
Thoracic Vertebrae - surgery
Tomography Scanners, X-Ray Computed
Treatment Outcome
title Surgical Technique for Decompression of Severe Thoracic Myelopathy due to Tuberous Ossification of Ligamentum Flavum
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T23%3A19%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Surgical%20Technique%20for%20Decompression%20of%20Severe%20Thoracic%20Myelopathy%20due%20to%20Tuberous%20Ossification%20of%20Ligamentum%20Flavum&rft.jtitle=Clinical%20spine%20surgery&rft.au=Wang,%20Ting&rft.date=2017-02-01&rft.volume=30&rft.issue=1&rft.spage=E7&rft.epage=E12&rft.pages=E7-E12&rft.issn=2380-0186&rft.eissn=2380-0194&rft_id=info:doi/10.1097/BSD.0000000000000213&rft_dat=%3Cproquest_cross%3E1861586921%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1861586921&rft_id=info:pmid/28107236&rfr_iscdi=true