Lupinus albus Conglutin Gamma Modifies the Gene Expressions of Enzymes Involved in Glucose Hepatic Production In Vivo

Lupinus albus seeds contain conglutin gamma (Cγ) protein, which exerts a hypoglycemic effect and positively modifies proteins involved in glucose homeostasis. Cγ could potentially be used to manage patients with impaired glucose metabolism, but there remains a need to evaluate its effects on hepatic...

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Veröffentlicht in:	Plant foods for human nutrition (Dordrecht) 2017-06, Vol.72 (2), p.134-140
Hauptverfasser:	González-Santiago, Ana E., Vargas-Guerrero, Belinda, García-López, Pedro M., Martínez-Ayala, Alma L., Domínguez-Rosales, José A., Gurrola-Díaz, Carmen M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal models Animals Biochemistry Blood Glucose - drug effects Chemistry Chemistry and Materials Science Chemistry/Food Science Colorimetry Diabetes mellitus Diabetes Mellitus, Experimental - chemically induced Diabetes Mellitus, Experimental - drug therapy Diabetes Mellitus, Type 2 - drug therapy Disease Models, Animal Disorders DNA-Binding Proteins - drug effects DNA-Binding Proteins - metabolism Ecology Enzymes Food Science Gene expression Gene Expression - drug effects Glucose Glucose metabolism Glucose-6-Phosphatase - drug effects Glucose-6-Phosphatase - metabolism Homeostasis Hypoglycemic Agents - administration & dosage Insulin Insulin - metabolism Insulin Resistance Integrity Intracellular Signaling Peptides and Proteins - drug effects Intracellular Signaling Peptides and Proteins - metabolism Kidney - drug effects Kidneys Liver Liver - drug effects Lupinus - chemistry Male Mathematical models Metabolism Metformin Nutrition Oral cavity Original Paper Patients Phosphoenolpyruvate Carboxykinase (GTP) - drug effects Phosphoenolpyruvate Carboxykinase (GTP) - metabolism Plant Physiology Plant Proteins - administration & dosage Polymerase chain reaction Proteins Rats Rats, Wistar Real time Rodents Seeds Seeds - chemistry Sodium chloride Streptozocin Streptozocin - adverse effects Subgroups Sucrose Sugar
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