Safety and feasibility of PCI in patients undergoing TAVR: A systematic review and meta-analysis
Abstract We aimed to evaluate the safety and feasibility of PCI (percutaneous coronary intervention) for coronary artery disease (CAD) in patients undergoing transcatheter aortic valve replacement (TAVR) by performing a meta-analysis. A systemic search of the database was performed. Studies were inc...
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| Veröffentlicht in: | Heart & lung 2017-03, Vol.46 (2), p.92-99 |
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| creator | Bajaj, Anurag, MD, FACP Pancholy, Samir, MD, FACC, FSCAI Sethi, Arjinder, MD, FACP Rathor, Parul, MBBS |
| description | Abstract We aimed to evaluate the safety and feasibility of PCI (percutaneous coronary intervention) for coronary artery disease (CAD) in patients undergoing transcatheter aortic valve replacement (TAVR) by performing a meta-analysis. A systemic search of the database was performed. Studies were included comparing TAVR versus TAVR with PCI for significant CAD in patients undergoing TAVR for severe aortic stenosis. The primary outcome was 30 day mortality and secondary outcomes were myocardial infarction, stroke, life threatening bleeding, major access site vascular complications and renal failure. There were no significant differences in 30 day and six months-one year mortality between TAVR and TAVR with PCI group. There were also no significant differences in myocardial infarction, stroke, and life threatening bleeding and major access site vascular complications between the two groups. PCI in addition to TAVR in patients with concomitant severe aortic stenosis and CAD is safe and feasible and does not increase procedural risk. |
| doi_str_mv | 10.1016/j.hrtlng.2016.12.003 |
| format | Article |
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A systemic search of the database was performed. Studies were included comparing TAVR versus TAVR with PCI for significant CAD in patients undergoing TAVR for severe aortic stenosis. The primary outcome was 30 day mortality and secondary outcomes were myocardial infarction, stroke, life threatening bleeding, major access site vascular complications and renal failure. There were no significant differences in 30 day and six months-one year mortality between TAVR and TAVR with PCI group. There were also no significant differences in myocardial infarction, stroke, and life threatening bleeding and major access site vascular complications between the two groups. PCI in addition to TAVR in patients with concomitant severe aortic stenosis and CAD is safe and feasible and does not increase procedural risk.</description><identifier>ISSN: 0147-9563</identifier><identifier>EISSN: 1527-3288</identifier><identifier>DOI: 10.1016/j.hrtlng.2016.12.003</identifier><identifier>PMID: 28088437</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Aortic stenosis ; Aortic Valve - surgery ; Aortic Valve Stenosis - complications ; Aortic Valve Stenosis - diagnosis ; Cardiovascular ; Coronary artery disease ; Coronary Artery Disease - complications ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - surgery ; Critical Care ; Feasibility Studies ; Global Health ; Humans ; Kaplan-Meier Estimate ; Mortality ; Percutaneous coronary intervention ; Percutaneous Coronary Intervention - methods ; Pulmonary/Respiratory ; Severity of Illness Index ; Survival Rate - trends ; Transcatheter Aortic Valve Replacement ; Treatment Outcome</subject><ispartof>Heart & lung, 2017-03, Vol.46 (2), p.92-99</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c483t-caccf958ac3d731d8de4f70bdc6dd567b15e1c3fe160472f849de5676f3cd17f3</citedby><cites>FETCH-LOGICAL-c483t-caccf958ac3d731d8de4f70bdc6dd567b15e1c3fe160472f849de5676f3cd17f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.hrtlng.2016.12.003$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28088437$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bajaj, Anurag, MD, FACP</creatorcontrib><creatorcontrib>Pancholy, Samir, MD, FACC, FSCAI</creatorcontrib><creatorcontrib>Sethi, Arjinder, MD, FACP</creatorcontrib><creatorcontrib>Rathor, Parul, MBBS</creatorcontrib><title>Safety and feasibility of PCI in patients undergoing TAVR: A systematic review and meta-analysis</title><title>Heart & lung</title><addtitle>Heart Lung</addtitle><description>Abstract We aimed to evaluate the safety and feasibility of PCI (percutaneous coronary intervention) for coronary artery disease (CAD) in patients undergoing transcatheter aortic valve replacement (TAVR) by performing a meta-analysis. A systemic search of the database was performed. Studies were included comparing TAVR versus TAVR with PCI for significant CAD in patients undergoing TAVR for severe aortic stenosis. The primary outcome was 30 day mortality and secondary outcomes were myocardial infarction, stroke, life threatening bleeding, major access site vascular complications and renal failure. There were no significant differences in 30 day and six months-one year mortality between TAVR and TAVR with PCI group. There were also no significant differences in myocardial infarction, stroke, and life threatening bleeding and major access site vascular complications between the two groups. PCI in addition to TAVR in patients with concomitant severe aortic stenosis and CAD is safe and feasible and does not increase procedural risk.</description><subject>Aortic stenosis</subject><subject>Aortic Valve - surgery</subject><subject>Aortic Valve Stenosis - complications</subject><subject>Aortic Valve Stenosis - diagnosis</subject><subject>Cardiovascular</subject><subject>Coronary artery disease</subject><subject>Coronary Artery Disease - complications</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Coronary Artery Disease - surgery</subject><subject>Critical Care</subject><subject>Feasibility Studies</subject><subject>Global Health</subject><subject>Humans</subject><subject>Kaplan-Meier Estimate</subject><subject>Mortality</subject><subject>Percutaneous coronary intervention</subject><subject>Percutaneous Coronary Intervention - methods</subject><subject>Pulmonary/Respiratory</subject><subject>Severity of Illness Index</subject><subject>Survival Rate - trends</subject><subject>Transcatheter Aortic Valve Replacement</subject><subject>Treatment Outcome</subject><issn>0147-9563</issn><issn>1527-3288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU2P0zAQhi0EYsvCP0DIRy4J_khslwNSVfGx0kogduFqXHtcXBKn2A4o_x6XLhy44Is1o_ed0fsMQk8paSmh4sWh_ZrKEPctq1VLWUsIv4dWtGey4Uyp-2hFaCebdS_4BXqU84HUx4V8iC6YIkp1XK7QlxvjoSzYRIc9mBx2YQi1njz-sL3CIeKjKQFiyXiODtJ-CnGPbzefP77EG5yXXGCsAosT_Ajw8_ecEYppTDTDkkN-jB54M2R4cvdfok9vXt9u3zXX799ebTfXje0UL4011vp1r4zlTnLqlIPOS7JzVjjXC7mjPVDLPVBBOsm86tYOal94bh2Vnl-i5-e5xzR9nyEXPYZsYRhMhGnOmipB-44yTqq0O0ttmnJO4PUxhdGkRVOiT2z1QZ_Z6hNbTZmu4Krt2d2GeTeC-2v6A7MKXp0FUHNWGklnW9FZcCGBLdpN4X8b_h1ghxCDNcM3WCAfpjlVqjWLztWgb073PZ2XippKrRn_BdRFoh8</recordid><startdate>20170301</startdate><enddate>20170301</enddate><creator>Bajaj, Anurag, MD, FACP</creator><creator>Pancholy, Samir, MD, FACC, FSCAI</creator><creator>Sethi, Arjinder, MD, FACP</creator><creator>Rathor, Parul, MBBS</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20170301</creationdate><title>Safety and feasibility of PCI in patients undergoing TAVR: A systematic review and meta-analysis</title><author>Bajaj, Anurag, MD, FACP ; Pancholy, Samir, MD, FACC, FSCAI ; Sethi, Arjinder, MD, FACP ; Rathor, Parul, MBBS</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c483t-caccf958ac3d731d8de4f70bdc6dd567b15e1c3fe160472f849de5676f3cd17f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Aortic stenosis</topic><topic>Aortic Valve - surgery</topic><topic>Aortic Valve Stenosis - complications</topic><topic>Aortic Valve Stenosis - diagnosis</topic><topic>Cardiovascular</topic><topic>Coronary artery disease</topic><topic>Coronary Artery Disease - complications</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Coronary Artery Disease - surgery</topic><topic>Critical Care</topic><topic>Feasibility Studies</topic><topic>Global Health</topic><topic>Humans</topic><topic>Kaplan-Meier Estimate</topic><topic>Mortality</topic><topic>Percutaneous coronary intervention</topic><topic>Percutaneous Coronary Intervention - methods</topic><topic>Pulmonary/Respiratory</topic><topic>Severity of Illness Index</topic><topic>Survival Rate - trends</topic><topic>Transcatheter Aortic Valve Replacement</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bajaj, Anurag, MD, FACP</creatorcontrib><creatorcontrib>Pancholy, Samir, MD, FACC, FSCAI</creatorcontrib><creatorcontrib>Sethi, Arjinder, MD, FACP</creatorcontrib><creatorcontrib>Rathor, Parul, MBBS</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Heart & lung</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bajaj, Anurag, MD, FACP</au><au>Pancholy, Samir, MD, FACC, FSCAI</au><au>Sethi, Arjinder, MD, FACP</au><au>Rathor, Parul, MBBS</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Safety and feasibility of PCI in patients undergoing TAVR: A systematic review and meta-analysis</atitle><jtitle>Heart & lung</jtitle><addtitle>Heart Lung</addtitle><date>2017-03-01</date><risdate>2017</risdate><volume>46</volume><issue>2</issue><spage>92</spage><epage>99</epage><pages>92-99</pages><issn>0147-9563</issn><eissn>1527-3288</eissn><abstract>Abstract We aimed to evaluate the safety and feasibility of PCI (percutaneous coronary intervention) for coronary artery disease (CAD) in patients undergoing transcatheter aortic valve replacement (TAVR) by performing a meta-analysis. A systemic search of the database was performed. Studies were included comparing TAVR versus TAVR with PCI for significant CAD in patients undergoing TAVR for severe aortic stenosis. The primary outcome was 30 day mortality and secondary outcomes were myocardial infarction, stroke, life threatening bleeding, major access site vascular complications and renal failure. There were no significant differences in 30 day and six months-one year mortality between TAVR and TAVR with PCI group. There were also no significant differences in myocardial infarction, stroke, and life threatening bleeding and major access site vascular complications between the two groups. PCI in addition to TAVR in patients with concomitant severe aortic stenosis and CAD is safe and feasible and does not increase procedural risk.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>28088437</pmid><doi>10.1016/j.hrtlng.2016.12.003</doi><tpages>8</tpages></addata></record> |
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| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Aortic stenosis Aortic Valve - surgery Aortic Valve Stenosis - complications Aortic Valve Stenosis - diagnosis Cardiovascular Coronary artery disease Coronary Artery Disease - complications Coronary Artery Disease - diagnosis Coronary Artery Disease - surgery Critical Care Feasibility Studies Global Health Humans Kaplan-Meier Estimate Mortality Percutaneous coronary intervention Percutaneous Coronary Intervention - methods Pulmonary/Respiratory Severity of Illness Index Survival Rate - trends Transcatheter Aortic Valve Replacement Treatment Outcome |
| title | Safety and feasibility of PCI in patients undergoing TAVR: A systematic review and meta-analysis |
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