Lemierre's Syndrome as a Trigger for Secondary Hemophagocytic Lymphohistiocytosis

Secondary hemophagocytic lymphohistiocytosis (sHLH) is a rare hyperinflammatory disorder caused by an aberrant immune response to a number of infectious or inflammatory conditions. Successful treatment of this potentially fatal condition requires early recognition and prompt therapy directed at the...

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Veröffentlicht in:Journal of pediatric hematology/oncology 2017-08, Vol.39 (6), p.e325-e327
Hauptverfasser: Kumral, Abigail V W, Petersen, Jr, William C, Heitz, Christopher, Waggoner-Fountain, Linda A, Belyea, Brian C
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container_issue 6
container_start_page e325
container_title Journal of pediatric hematology/oncology
container_volume 39
creator Kumral, Abigail V W
Petersen, Jr, William C
Heitz, Christopher
Waggoner-Fountain, Linda A
Belyea, Brian C
description Secondary hemophagocytic lymphohistiocytosis (sHLH) is a rare hyperinflammatory disorder caused by an aberrant immune response to a number of infectious or inflammatory conditions. Successful treatment of this potentially fatal condition requires early recognition and prompt therapy directed at the underlying trigger. In this report, we describe the clinical presentation, diagnostic findings, management, and outcome of a child with Lemierre's syndrome-associated sHLH. This is the first reported association of these 2 rare conditions and expands the number of known triggers for sHLH.
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subjects Adolescent
Diagnosis, Differential
Disease Management
Female
Humans
Lemierre Syndrome - complications
Lymphohistiocytosis, Hemophagocytic - diagnosis
Lymphohistiocytosis, Hemophagocytic - etiology
Lymphohistiocytosis, Hemophagocytic - therapy
Treatment Outcome
title Lemierre's Syndrome as a Trigger for Secondary Hemophagocytic Lymphohistiocytosis
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