A highly sensitive quantum dots-DNA nanobiosensor based on fluorescence resonance energy transfer for rapid detection of nanomolar amounts of human papillomavirus 18

[Display omitted] •Design of a highly selective and sensitive FRET-based nanobiosensor for low level detection of HPV18.•Use of TGA-CdTe quantum dots as donor and fluorophore Cy5-labeled oligonucleotides as acceptor.•Obtaining a linear range of 1–50nM with a detection limit of 0.2nM.•Successful appl...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2017-03, Vol.136, p.140-147
Hauptverfasser:	Shamsipur, Mojtaba, Nasirian, Vahid, Mansouri, Kamran, Barati, Ali, Veisi-Raygani, Asad, Kashanian, Soheila
Format:	Artikel
Sprache:	eng
Schlagworte:	Biosensing Techniques - instrumentation Biosensing Techniques - methods Cadmium Compounds - chemistry DNA DNA, Viral - analysis DNA, Viral - genetics Fluorescence resonance energy transfer Fluorescence Resonance Energy Transfer - instrumentation Fluorescence Resonance Energy Transfer - methods Human papillomavirus 18 Human papillomavirus 18 - genetics Nanobiosensor Nanotechnology - instrumentation Nanotechnology - methods Oligonucleotides - chemistry Quantum dots Quantum Dots - chemistry Reproducibility of Results Sensitivity and Specificity Tellurium - chemistry Thioglycolates - chemistry
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