Sulfation of fucogalactan from Agaricus bisporus: Different patterns in the chemical structure and their effects on anticoagulant activity

A fucogalactan from Agaricus bisporus was sulfated by two methodologies based on an optimized sulfation method. The direct action of chlorosulfonic acid and SO3-pyridine complex over the sulfation reaction and its effects on anticoagulant activity were evaluated. The products of chemical sulfations...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of biological macromolecules 2017-04, Vol.97, p.357-364
Hauptverfasser:	Román Ochoa, Yony, Iacomini, Marcello, Sassaki, Guilherme Lanzi, Cipriani, Thales Ricardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Agaricus - chemistry Animals Anticoagulant Anticoagulants - chemistry Anticoagulants - pharmacology Blood Coagulation - drug effects Chemical sulfation Factor Xa - metabolism Factor XIIa - metabolism Fucogalactan Galactans - chemistry Galactans - pharmacology Partial Thromboplastin Time Sheep Structure-Activity Relationship Sulfates - chemistry Thrombin - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!