The dual role of cathelicidins in systemic inflammation

Highlights • Antimicrobial peptides are key components of the innate immune system. • Cathelicidins are a class of antimicrobial peptide found in humans, mice, and rats, among others. • The role of cathelicidins is somewhat confounding, as they exhibit both pro-and anti-inflammatory activity. A majo...

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Veröffentlicht in:	Immunology letters 2017-02, Vol.182, p.57-60
Hauptverfasser:	Silva, Fabiano Pinheiro da, MD PhD, Machado, Marcel Cerqueira César
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Animals Cathelicidins - genetics Cathelicidins - metabolism CRAMP Cytokines - metabolism Gene Expression Regulation Humans Inflammation Inflammation - etiology Inflammation - metabolism Inflammation Mediators - metabolism LL-37 Sepsis Signal Transduction
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