Genotoxicity risk assessment: a proposed classification strategy

Recent advances in genetic toxicity (mutagenicity) testing methods and in approaches to performing risk assessment are prompting a renewed effort to harmonize genotoxicity risk assessment across the world. The US Environmental Protection Agency (EPA) first published Guidelines for Mutagenicity Risk...

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Veröffentlicht in:	Mutation research 2002-11, Vol.521 (1), p.121-135
Hauptverfasser:	Dearfield, Kerry L, Cimino, Michael C, McCarroll, Nancy E, Mauer, Irving, Valcovic, Lawrence R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria - drug effects Bacteria - genetics Biological and medical sciences Dose-Response Relationship, Drug Environmental pollutants toxicology Genetic risk Genotoxicity risk assessment Guidelines as Topic Hazard assessment Medical sciences Mice Micronucleus Tests Mutagenicity classification Mutagenicity testing Mutagenicity Tests - methods Risk Assessment Test battery Toxicology United States United States Environmental Protection Agency - standards Water
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