Carotid artery plaques and intima medial thickness in familial hypercholesteraemic patients on long-term statin therapy: A case control study

Abstract Background and aims Statins reduce subclinical atherosclerosis and premature atherosclerotic cardiovascular disease (ASCVD) in patients with familial hypercholesterolemia (FH). However, some FH patients still develop ASCVD despite statin therapy. We compared subclinical atherosclerosis asse...

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Veröffentlicht in:	Atherosclerosis 2017-01, Vol.256, p.62-66
Hauptverfasser:	Bos, Sven, Duvekot, Martijne H.C, ten Kate, Gert-Jan R, Verhoeven, Adrie J.M, Mulder, Monique T, Schinkel, Arend F.L, Nieman, Koen, Watts, Gerald F, Sijbrands, Eric J.G, Roeters van Lennep, Jeanine E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Asymptomatic Diseases Cardiovascular Carotid Arteries - diagnostic imaging Carotid Arteries - pathology Carotid Artery Diseases - diagnostic imaging Carotid Artery Diseases - genetics Carotid Artery Diseases - pathology Carotid Intima-Media Thickness Carotid plaque presence Case-Control Studies Computed Tomography Angiography Coronary Angiography - methods Coronary Artery Disease - diagnostic imaging Coronary Artery Disease - genetics Familial hypercholesterolemia Female Genetic Predisposition to Disease Heterozygote Humans Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use Hyperlipoproteinemia Type II - complications Hyperlipoproteinemia Type II - diagnosis Hyperlipoproteinemia Type II - drug therapy Hyperlipoproteinemia Type II - genetics Male Middle Aged Phenotype Plaque, Atherosclerotic Predictive Value of Tests Residual risk Risk Factors Time Factors Treatment Outcome Vascular Calcification - diagnostic imaging Vascular Calcification - genetics
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