Biomechanical and endplate effects on nutrient transport in the intervertebral disc

Abstract Background Physical data are lacking on nutrient transport in human intervertebral discs (IVDs), which supports regeneration. Our objective was to study nutrient transport in porcine IVDs to determine the effects of biomechanical and physiological factors. Methods In vitro testing of whole...

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Veröffentlicht in:	World neurosurgery 2017-03, Vol.99, p.395-402
Hauptverfasser:	Giers, Morgan B., PhD, Munter, Bryce T., MS, Eyster, Kyle J., MS, Ide, George D., MD, Newcomb, Anna G.U.S., MS, Lehrman, Jennifer N., MS, Belykh, Evgenii, MD, Byvaltsev, Vadim A., MD PhD, Kelly, Brian P., PhD, Preul, Mark C., MD, Theodore, Nicholas, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Annulus fibrosus Annulus Fibrosus - metabolism Annulus Fibrosus - physiology Biological Transport - physiology Biomechanical Phenomena Biomechanics Calcification Cell function Extracellular matrix Glucose - metabolism In Vitro Techniques Intervertebral disc Intervertebral Disc - metabolism Intervertebral Disc - physiology Neurosurgery Nucleus pulposus Nucleus Pulposus - metabolism Nucleus Pulposus - physiology Nutrient transport Regeneration Regeneration - physiology Spine Stress, Mechanical Sus scrofa Swine
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