Hippocampal Neural Disinhibition Causes Attentional and Memory Deficits

Subconvulsive hippocampal neural disinhibition, that is reduced GABAergic inhibition, has been implicated in neuropsychiatric disorders characterized by attentional and memory deficits, including schizophrenia and age-related cognitive decline. Considering that neural disinhibition may disrupt both...

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Veröffentlicht in:	Cerebral cortex (New York, N.Y. 1991) N.Y. 1991), 2017-09, Vol.27 (9), p.4447-4462
Hauptverfasser:	McGarrity, Stephanie, Mason, Rob, Fone, Kevin C, Pezze, Marie, Bast, Tobias
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Attention Deficit Disorder with Hyperactivity - physiopathology GABA-A Receptor Antagonists - pharmacology Hippocampus - drug effects Hippocampus - physiology Male Memory Disorders - physiopathology Neural Inhibition - physiology Neurons - drug effects Picrotoxin - pharmacology Rats Reflex, Startle - drug effects
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