Synthesis and basic evaluation of 7α-(3-[18F]fluoropropyl)-testosterone and 7α-(3-[18F]fluoropropyl)-dihydrotestosterone

Objective 7α-Substituted androgen derivatives may have the potential to visualize androgen receptors with positron emission tomography. In the present study, we synthesized fluoropropyl derivatives of 7α-(3-[ 18 F]fluoropropyl)-testosterone ([ 18 F] 7 ) and 7α-(3-[ 18 F]fluoropropyl)-dihydrotestoste...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Annals of nuclear medicine 2017, Vol.31 (1), p.53-62
Hauptverfasser:	Okamoto, Mayumi, Naka, Kyosuke, Ishiwata, Kiichi, Shimizu, Isao, Toyohara, Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens - deficiency Animals Chemistry Techniques, Synthetic Dihydrotestosterone - chemical synthesis Dihydrotestosterone - chemistry Dihydrotestosterone - metabolism Dihydrotestosterone - pharmacokinetics Imaging Male Medicine Medicine & Public Health Nuclear Medicine Original Article Radiochemistry Radiology Rats Receptors, Androgen - metabolism Testosterone - analogs & derivatives Testosterone - chemical synthesis Testosterone - chemistry Testosterone - metabolism Testosterone - pharmacokinetics Tissue Distribution
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!