Formulation of orodispersible films for paediatric therapy: investigation of feasibility and stability for tetrabenazine as drug model

Objectives Orodispersible films (ODF) were formulated to facilitate tetrabenazine (TBZ) administration to paediatric population for the treatment of hyperkinetic movement disorders. Methods ODF were obtained by solvent casting/evaporation method using four different polymers (HPMC, PVP, pullulan and...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of pharmacy and pharmacology 2017-05, Vol.69 (5), p.582-592
Hauptverfasser:	Senta‐Loys, Zoé, Bourgeois, Sandrine, Pailler‐Mattei, Cyril, Agusti, Géraldine, Briançon, Stéphanie, Fessi, Hatem
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Buccal Administration, Oral Chemistry, Pharmaceutical - methods Drug Liberation - drug effects Drug Stability HPMC Humans Hyperkinesis - drug therapy Oral Mucosal Absorption orodispersible film paediatric medicine Polymers - chemistry PVP Saliva - metabolism Solubility Solvents - chemistry tetrabenazine Tetrabenazine - administration & dosage Tetrabenazine - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!