Analysis of clinical and pathological characteristics of high- risk HPV-negative carcinoma of the uterine cervix
To study the clinical and pathological characteristics of HPV-negative cervical cancer patients. Retrospective analysis of 785 cervical cancer patients in Guangdong Women and Children Hospital from Jan. 2005 to Oct. 2015. By detecting high- risk HPV infection by flow-through hybridization genechip t...
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| Veröffentlicht in: | Chung-hua fu chʿan kʿo tsa chih 2016-09, Vol.51 (9), p.683-687 |
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| container_title | Chung-hua fu chʿan kʿo tsa chih |
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| creator | Li, Z M Zeng, L Q Peng, X H Mao, L Z Sun, X L Li, Y H Luo, X P |
| description | To study the clinical and pathological characteristics of HPV-negative cervical cancer patients.
Retrospective analysis of 785 cervical cancer patients in Guangdong Women and Children Hospital from Jan. 2005 to Oct. 2015. By detecting high- risk HPV infection by flow-through hybridization genechip technique.
(1)Among 785 cases of cervical cancer, 71 cases were negative for HPV infection tested by genechip technique, accounting for 9.0%(71/785), and the relative light units/cut off(RLU/CO)ratios of these 71 cases were less than 1 by hybird capture Ⅱ(HC-Ⅱ)methods. The results showed that the positive coincident rate of genechip technique detecting result with HC-Ⅱ method was 100.0%(71/71).(2)There was no difference between 43(60.6%)cases from 41-55 years old of 71 cases of HPV-negative patients and 392(54.9%)cases from 41- 55 years old of 714 cases of HPV infection patients(
=15.63,
=0.571). Among 71 cases of HPV-negative patients, 32 cases of patients with doing TCT, 6(18.8%)cases for normal, 10(31.2%)cases fo |
| doi_str_mv | 10.3760/cma.j.issn.0529-567X.2016.09.009 |
| format | Article |
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Retrospective analysis of 785 cervical cancer patients in Guangdong Women and Children Hospital from Jan. 2005 to Oct. 2015. By detecting high- risk HPV infection by flow-through hybridization genechip technique.
(1)Among 785 cases of cervical cancer, 71 cases were negative for HPV infection tested by genechip technique, accounting for 9.0%(71/785), and the relative light units/cut off(RLU/CO)ratios of these 71 cases were less than 1 by hybird capture Ⅱ(HC-Ⅱ)methods. The results showed that the positive coincident rate of genechip technique detecting result with HC-Ⅱ method was 100.0%(71/71).(2)There was no difference between 43(60.6%)cases from 41-55 years old of 71 cases of HPV-negative patients and 392(54.9%)cases from 41- 55 years old of 714 cases of HPV infection patients(
=15.63,
=0.571). Among 71 cases of HPV-negative patients, 32 cases of patients with doing TCT, 6(18.8%)cases for normal, 10(31.2%)cases fo</description><identifier>ISSN: 0529-567X</identifier><identifier>DOI: 10.3760/cma.j.issn.0529-567X.2016.09.009</identifier><identifier>PMID: 27671050</identifier><language>chi</language><publisher>China</publisher><subject>Adult ; Carcinoma, Squamous Cell ; Cytodiagnosis ; Female ; Humans ; Middle Aged ; Papillomaviridae ; Papillomavirus Infections ; Retrospective Studies ; Risk Factors ; Uterine Cervical Neoplasms</subject><ispartof>Chung-hua fu chʿan kʿo tsa chih, 2016-09, Vol.51 (9), p.683-687</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27671050$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Li, Z M</creatorcontrib><creatorcontrib>Zeng, L Q</creatorcontrib><creatorcontrib>Peng, X H</creatorcontrib><creatorcontrib>Mao, L Z</creatorcontrib><creatorcontrib>Sun, X L</creatorcontrib><creatorcontrib>Li, Y H</creatorcontrib><creatorcontrib>Luo, X P</creatorcontrib><title>Analysis of clinical and pathological characteristics of high- risk HPV-negative carcinoma of the uterine cervix</title><title>Chung-hua fu chʿan kʿo tsa chih</title><addtitle>Zhonghua Fu Chan Ke Za Zhi</addtitle><description>To study the clinical and pathological characteristics of HPV-negative cervical cancer patients.
Retrospective analysis of 785 cervical cancer patients in Guangdong Women and Children Hospital from Jan. 2005 to Oct. 2015. By detecting high- risk HPV infection by flow-through hybridization genechip technique.
(1)Among 785 cases of cervical cancer, 71 cases were negative for HPV infection tested by genechip technique, accounting for 9.0%(71/785), and the relative light units/cut off(RLU/CO)ratios of these 71 cases were less than 1 by hybird capture Ⅱ(HC-Ⅱ)methods. The results showed that the positive coincident rate of genechip technique detecting result with HC-Ⅱ method was 100.0%(71/71).(2)There was no difference between 43(60.6%)cases from 41-55 years old of 71 cases of HPV-negative patients and 392(54.9%)cases from 41- 55 years old of 714 cases of HPV infection patients(
=15.63,
=0.571). Among 71 cases of HPV-negative patients, 32 cases of patients with doing TCT, 6(18.8%)cases for normal, 10(31.2%)cases fo</description><subject>Adult</subject><subject>Carcinoma, Squamous Cell</subject><subject>Cytodiagnosis</subject><subject>Female</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Papillomaviridae</subject><subject>Papillomavirus Infections</subject><subject>Retrospective Studies</subject><subject>Risk Factors</subject><subject>Uterine Cervical Neoplasms</subject><issn>0529-567X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kMtOwzAQRb0A0ar0F5CX3ST4UdvxsqqAIlWCBSB20cRxGkPihDip6N-TlsJqpHPPjHQHoQUlMVeS3Joa4o_YheBjIpiOhFTvMSNUxkTHhOgLNP3nEzQPwWVEUC4TRvUVmjAlFSWCTFG78lAdggu4KbCpnHcGKgw-xy30ZVM1uxMwJXRgetu50Dtzkku3KyM8gk-8eX6LvN1B7_YWG-iM800NR6kvLR6Oa34MbLd339fosoAq2Pl5ztDr_d3LehNtnx4e16tt1FIm-2iZL6lZ5mYsYXnOgDIrWaI011KBylguNBSS8uxYWoqkSHQyxoZwCTrnks_Q4vdu2zVfgw19WrtgbFWBt80QUpoIrZighI_qzVkdstrmadu5GrpD-vcl_gO3Em19</recordid><startdate>20160925</startdate><enddate>20160925</enddate><creator>Li, Z M</creator><creator>Zeng, L Q</creator><creator>Peng, X H</creator><creator>Mao, L Z</creator><creator>Sun, X L</creator><creator>Li, Y H</creator><creator>Luo, X P</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20160925</creationdate><title>Analysis of clinical and pathological characteristics of high- risk HPV-negative carcinoma of the uterine cervix</title><author>Li, Z M ; Zeng, L Q ; Peng, X H ; Mao, L Z ; Sun, X L ; Li, Y H ; Luo, X P</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p126t-4d41c4dc529e3d2a12e628793967a7b2d59af613b2016658f898879c036a9d363</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>chi</language><creationdate>2016</creationdate><topic>Adult</topic><topic>Carcinoma, Squamous Cell</topic><topic>Cytodiagnosis</topic><topic>Female</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Papillomaviridae</topic><topic>Papillomavirus Infections</topic><topic>Retrospective Studies</topic><topic>Risk Factors</topic><topic>Uterine Cervical Neoplasms</topic><toplevel>online_resources</toplevel><creatorcontrib>Li, Z M</creatorcontrib><creatorcontrib>Zeng, L Q</creatorcontrib><creatorcontrib>Peng, X H</creatorcontrib><creatorcontrib>Mao, L Z</creatorcontrib><creatorcontrib>Sun, X L</creatorcontrib><creatorcontrib>Li, Y H</creatorcontrib><creatorcontrib>Luo, X P</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Chung-hua fu chʿan kʿo tsa chih</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Z M</au><au>Zeng, L Q</au><au>Peng, X H</au><au>Mao, L Z</au><au>Sun, X L</au><au>Li, Y H</au><au>Luo, X P</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Analysis of clinical and pathological characteristics of high- risk HPV-negative carcinoma of the uterine cervix</atitle><jtitle>Chung-hua fu chʿan kʿo tsa chih</jtitle><addtitle>Zhonghua Fu Chan Ke Za Zhi</addtitle><date>2016-09-25</date><risdate>2016</risdate><volume>51</volume><issue>9</issue><spage>683</spage><epage>687</epage><pages>683-687</pages><issn>0529-567X</issn><abstract>To study the clinical and pathological characteristics of HPV-negative cervical cancer patients.
Retrospective analysis of 785 cervical cancer patients in Guangdong Women and Children Hospital from Jan. 2005 to Oct. 2015. By detecting high- risk HPV infection by flow-through hybridization genechip technique.
(1)Among 785 cases of cervical cancer, 71 cases were negative for HPV infection tested by genechip technique, accounting for 9.0%(71/785), and the relative light units/cut off(RLU/CO)ratios of these 71 cases were less than 1 by hybird capture Ⅱ(HC-Ⅱ)methods. The results showed that the positive coincident rate of genechip technique detecting result with HC-Ⅱ method was 100.0%(71/71).(2)There was no difference between 43(60.6%)cases from 41-55 years old of 71 cases of HPV-negative patients and 392(54.9%)cases from 41- 55 years old of 714 cases of HPV infection patients(
=15.63,
=0.571). Among 71 cases of HPV-negative patients, 32 cases of patients with doing TCT, 6(18.8%)cases for normal, 10(31.2%)cases fo</abstract><cop>China</cop><pmid>27671050</pmid><doi>10.3760/cma.j.issn.0529-567X.2016.09.009</doi><tpages>5</tpages></addata></record> |
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| language | chi |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Carcinoma, Squamous Cell Cytodiagnosis Female Humans Middle Aged Papillomaviridae Papillomavirus Infections Retrospective Studies Risk Factors Uterine Cervical Neoplasms |
| title | Analysis of clinical and pathological characteristics of high- risk HPV-negative carcinoma of the uterine cervix |
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