The influence of titanium surface characteristics on macrophage phenotype polarization during osseous healing in type I diabetic rats: a pilot study

Objectives This study assessed the effect of titanium surface modification on macrophage phenotype polarization and osseous healing under diabetic conditions. Materials and methods Critical‐sized calvarial defects were created in healthy and streptozotocin‐induced type I diabetic Sprague‐Dawley rats...

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Veröffentlicht in:	Clinical oral implants research 2017-10, Vol.28 (10), p.e159-e168
Hauptverfasser:	Lee, Ryan S. B., Hamlet, Stephen M., Ivanovski, Saso
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bone growth Bone-Implant Interface bone–implant interactions CD11c antigen CD163 antigen Cytokines Defects Dentistry Diabetes Diabetes mellitus Diabetes Mellitus, Experimental - immunology Diabetes Mellitus, Type 1 - immunology Enzyme-linked immunosorbent assay Exudation Female Fluorescence GBR Genotype & phenotype Grit Healing Inflammation Macrophage inflammatory protein Macrophages Macrophages - physiology Monocyte chemoattractant protein 1 Osteogenesis Phenotype Pilot Projects Polarization Rats Rats, Sprague-Dawley Rodents Staining Statistical analysis Statistical methods Streptozocin surface chemistry/hydrophilicity Surface Properties Surgery Titanium
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