Immunoprofile of the adenomatoid odontogenic tumor

This study was focused on the immunohistochemical profile of the adenomatoid odontogenic tumor. A Pub/Medline search revealed a number of immunohistochemical studies including cytokeratin profiles, extracellular matrix proteins, Integrins, ameloblast‐associated proteins resorption regulators (RANK,...

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Veröffentlicht in:	Oral diseases 2017-09, Vol.23 (6), p.731-736
Hauptverfasser:	Reichart, PA, Philipsen, HP, Khongkhunthian, P, Sciubba, JJ
Format:	Artikel
Sprache:	eng
Schlagworte:	adenomatoid odontogenic tumor Ameloblastoma - metabolism Dentistry DNA Modification Methylases - metabolism Extracellular Matrix Proteins - metabolism hamartoma Humans Immunohistochemistry Intercellular Signaling Peptides and Proteins - metabolism Jaw Neoplasms - metabolism Keratins - metabolism Membrane Proteins - metabolism Metalloproteases - metabolism Metallothionein - metabolism neoplasm Neoplasm Proteins - metabolism Nuclear Proteins - metabolism
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container_title	Oral diseases
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creator	Reichart, PA Philipsen, HP Khongkhunthian, P Sciubba, JJ
description	This study was focused on the immunohistochemical profile of the adenomatoid odontogenic tumor. A Pub/Medline search revealed a number of immunohistochemical studies including cytokeratin profiles, extracellular matrix proteins, Integrins, ameloblast‐associated proteins resorption regulators (RANK, RANKL), p53, PCNA, MDM2 protein, cyclin D1, Ki‐67, Bcl‐2 metallothionein, metalloproteinases, D56 hepatocyte growth factor, c‐met, DNA methyltransferase, podoplanin, TGF‐βI, Smad‐2/3, Smad‐I‐5/‐8, Smad 4, beta‐ catenin, calretinin, and clonality. Careful interpretation of the findings indicates that the adenomatoid odontogenic tumor may be more of a hamartomatous than neoplastic nature.
doi_str_mv	10.1111/odi.12572
format	Article
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subjects	adenomatoid odontogenic tumor Ameloblastoma - metabolism Dentistry DNA Modification Methylases - metabolism Extracellular Matrix Proteins - metabolism hamartoma Humans Immunohistochemistry Intercellular Signaling Peptides and Proteins - metabolism Jaw Neoplasms - metabolism Keratins - metabolism Membrane Proteins - metabolism Metalloproteases - metabolism Metallothionein - metabolism neoplasm Neoplasm Proteins - metabolism Nuclear Proteins - metabolism
title	Immunoprofile of the adenomatoid odontogenic tumor
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