Traumatic Brain Injury Results in Cellular, Structural and Functional Changes Resembling Motor Neuron Disease

Traumatic brain injury (TBI) has been suggested to increase the risk of amyotrophic lateral sclerosis (ALS). However, this link remains controversial and as such, here we performed experimental moderate TBI in rats and assessed for the presence of ALS-like pathological and functional abnormalities a...

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Veröffentlicht in:	Cerebral cortex (New York, N.Y. 1991) N.Y. 1991), 2017-09, Vol.27 (9), p.4503-4515
Hauptverfasser:	Wright, David K, Liu, Shijie, van der Poel, Chris, McDonald, Stuart J, Brady, Rhys D, Taylor, Lily, Yang, Li, Gardner, Andrew J, Ordidge, Roger, O'Brien, Terence J, Johnston, Leigh A, Shultz, Sandy R
Format:	Artikel
Sprache:	eng
Schlagworte:	Amyotrophic Lateral Sclerosis - physiopathology Animals Brain Injuries, Traumatic - complications Cytoplasm - metabolism Disease Models, Animal DNA-Binding Proteins - metabolism Male Motor Cortex - physiopathology Motor Neuron Disease - etiology Motor Neuron Disease - physiopathology Rats, Long-Evans Spinal Cord - physiopathology
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