No Association of Lower Hippocampal Volume With Alzheimer’s Disease Pathology in Late-Life Depression

Objective:Hippocampal volume is commonly decreased in late-life depression. According to the depression-as-late-life-neuropsychiatric-disorder model, lower hippocampal volume in late-life depression is associated with neurodegenerative changes. The purpose of this prospective study was to examine wh...

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Veröffentlicht in:	The American journal of psychiatry 2017-03, Vol.174 (3), p.237-245
Hauptverfasser:	De Winter, François-Laurent, Emsell, Louise, Bouckaert, Filip, Claes, Lene, Jain, Saurabh, Farrar, Gill, Billiet, Thibo, Evers, Stephan, Van den Stock, Jan, Sienaert, Pascal, Obbels, Jasmien, Sunaert, Stefan, Adamczuk, Katarzyna, Vandenberghe, Rik, Van Laere, Koen, Vandenbulcke, Mathieu
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - pathology Alzheimer's disease Amyloid - metabolism Aniline Compounds Atrophy Belgium Benzothiazoles Brain research Cerebral Cortex - pathology Depressive Disorder - pathology Female Fluorine Radioisotopes Hippocampus - pathology Humans Image Interpretation, Computer-Assisted Imaging, Three-Dimensional Magnetic Resonance Imaging Male Medical imaging Mental depression Middle Aged Neuropsychology Organ Size Positron-Emission Tomography Prodromal Symptoms Psychopathology Reference Values Statistics as Topic
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