Clinical Characteristics and Treatment Outcomes of Spinal Arteriovenous Malformations
Purpose Spinal arteriovenous malformations (SAVMs) are rare events. This study evaluated initial clinical presentations and treatment outcomes of SAVMs. Methods In this study, 91 consecutive patients with SAVM between January 1993 and November 2014 were evaluated. Initial clinical presentations, rad...
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| Veröffentlicht in: | Clinical neuroradiology (Munich) 2018-03, Vol.28 (1), p.39-46 |
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| creator | Park, Ji Eun Koo, Hae-Won Liu, Hairi Jung, Seung Chul Park, Danbi Suh, Dae Chul |
| description | Purpose
Spinal arteriovenous malformations (SAVMs) are rare events. This study evaluated initial clinical presentations and treatment outcomes of SAVMs.
Methods
In this study, 91 consecutive patients with SAVM between January 1993 and November 2014 were evaluated. Initial clinical presentations, radiological findings, treatment results, and follow-up outcomes were evaluated according to disease type and treatment modalities. Patient status was scored using the modified Rankin scale (mRS) and Aminoff–Logue Disability scale (ALS).
Results
Of the SAVM patients 69 % were male and 31 % were female with a mean age of 49 years (range 11–82 years). At the time of initial imaging evaluation, myelopathy was the most common finding with main complaints of gait disturbance (69 out of 91, 76 %), sensory disturbances (61/91, 67 %), and bowel or bladder symptoms (51/91, 56 %). Among the 80 patients who received treatment 56 (62 %) underwent endovascular embolization and 24 (26 %) underwent surgery. Complete obliteration was achieved in 47 patients (84 %) after endovascular embolization and in 18 (75 %) after surgical ligation. At the time of final follow-up 67 patients (84 %) showed improvement of more than 1 point on the mRS, while 69 (86 %) showed significant improvement on the ALS after treatment.
Conclusion
The SAVMs presented with diverse neurological deficits, including myelopathy. Endovascular or surgical treatment of SAVMs can result in good clinical outcomes in most patients. |
| doi_str_mv | 10.1007/s00062-016-0541-0 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1859714811</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A718271292</galeid><sourcerecordid>A718271292</sourcerecordid><originalsourceid>FETCH-LOGICAL-c439t-86de2aaa0ff9c6b0ff5fb131efd29555c81162f2bebd4be6c1187b2fc6bfddf93</originalsourceid><addsrcrecordid>eNp1kU9LHTEUxUOpVHn6AdyUgW66Gc3N_MnM8vFotWBxoa5DJnNjIzPJa5IR_Pa9j2eVSiWLhOR3DufmMHYK_Aw4l-eJc96KkkNb8qaGkn9gR9C1fQl1LT--nKv-kJ2k9EA0r7q-aeQndihkK4So5RG720zOO6OnYvNLR20yRpeyM6nQfixuI-o8o8_F9ZJNmDEVwRY3W-dJsI47ODyiD0sqfurJhjjr7IJPx-zA6inhyfO-Ynffv91uLsur64sfm_VVaShXLrt2RKG15tb2ph1oa-wAFaAdBSVtTAfQCisGHMZ6wNYAdHIQllg7jravVuzr3ncbw-8FU1azSwanSXukUAq6ppdQkw2hX96gD2GJNEdSgvNO9ryq5Ct1rydUztuQ6VN2pmotoRMSRC-IOvsPRWvE2Zng0Tq6_0cAe4GJIaWIVm2jm3V8UsDVrk21b1NRm2rXpuKk-fwceBlmHF8Uf7sjQOyBRE_-HuPrRO-7_gFgfKmE</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2008790337</pqid></control><display><type>article</type><title>Clinical Characteristics and Treatment Outcomes of Spinal Arteriovenous Malformations</title><source>MEDLINE</source><source>SpringerLink</source><creator>Park, Ji Eun ; Koo, Hae-Won ; Liu, Hairi ; Jung, Seung Chul ; Park, Danbi ; Suh, Dae Chul</creator><creatorcontrib>Park, Ji Eun ; Koo, Hae-Won ; Liu, Hairi ; Jung, Seung Chul ; Park, Danbi ; Suh, Dae Chul</creatorcontrib><description>Purpose
Spinal arteriovenous malformations (SAVMs) are rare events. This study evaluated initial clinical presentations and treatment outcomes of SAVMs.
Methods
In this study, 91 consecutive patients with SAVM between January 1993 and November 2014 were evaluated. Initial clinical presentations, radiological findings, treatment results, and follow-up outcomes were evaluated according to disease type and treatment modalities. Patient status was scored using the modified Rankin scale (mRS) and Aminoff–Logue Disability scale (ALS).
Results
Of the SAVM patients 69 % were male and 31 % were female with a mean age of 49 years (range 11–82 years). At the time of initial imaging evaluation, myelopathy was the most common finding with main complaints of gait disturbance (69 out of 91, 76 %), sensory disturbances (61/91, 67 %), and bowel or bladder symptoms (51/91, 56 %). Among the 80 patients who received treatment 56 (62 %) underwent endovascular embolization and 24 (26 %) underwent surgery. Complete obliteration was achieved in 47 patients (84 %) after endovascular embolization and in 18 (75 %) after surgical ligation. At the time of final follow-up 67 patients (84 %) showed improvement of more than 1 point on the mRS, while 69 (86 %) showed significant improvement on the ALS after treatment.
Conclusion
The SAVMs presented with diverse neurological deficits, including myelopathy. Endovascular or surgical treatment of SAVMs can result in good clinical outcomes in most patients.</description><identifier>ISSN: 1869-1439</identifier><identifier>EISSN: 1869-1447</identifier><identifier>DOI: 10.1007/s00062-016-0541-0</identifier><identifier>PMID: 27622247</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Adolescent ; Adult ; Aged ; Aged, 80 and over ; Arteriovenous malformations ; Arteriovenous Malformations - diagnosis ; Arteriovenous Malformations - pathology ; Arteriovenous Malformations - therapy ; Care and treatment ; Central Nervous System Vascular Malformations - diagnosis ; Central Nervous System Vascular Malformations - pathology ; Central Nervous System Vascular Malformations - therapy ; Child ; Clinical outcomes ; Embolization, Therapeutic ; Female ; Homeopathy ; Humans ; Male ; Materia medica and therapeutics ; Medical colleges ; Medical research ; Medicine ; Medicine & Public Health ; Medicine, Experimental ; Middle Aged ; Neurology ; Neuroradiology ; Neurosurgery ; Original Article ; Patient outcomes ; Retrospective Studies ; Therapeutics ; Treatment Outcome ; Young Adult</subject><ispartof>Clinical neuroradiology (Munich), 2018-03, Vol.28 (1), p.39-46</ispartof><rights>Springer-Verlag Berlin Heidelberg 2016</rights><rights>COPYRIGHT 2018 Springer</rights><rights>Clinical Neuroradiology is a copyright of Springer, (2016). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c439t-86de2aaa0ff9c6b0ff5fb131efd29555c81162f2bebd4be6c1187b2fc6bfddf93</citedby><cites>FETCH-LOGICAL-c439t-86de2aaa0ff9c6b0ff5fb131efd29555c81162f2bebd4be6c1187b2fc6bfddf93</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00062-016-0541-0$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00062-016-0541-0$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,41488,42557,51319</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27622247$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Park, Ji Eun</creatorcontrib><creatorcontrib>Koo, Hae-Won</creatorcontrib><creatorcontrib>Liu, Hairi</creatorcontrib><creatorcontrib>Jung, Seung Chul</creatorcontrib><creatorcontrib>Park, Danbi</creatorcontrib><creatorcontrib>Suh, Dae Chul</creatorcontrib><title>Clinical Characteristics and Treatment Outcomes of Spinal Arteriovenous Malformations</title><title>Clinical neuroradiology (Munich)</title><addtitle>Clin Neuroradiol</addtitle><addtitle>Clin Neuroradiol</addtitle><description>Purpose
Spinal arteriovenous malformations (SAVMs) are rare events. This study evaluated initial clinical presentations and treatment outcomes of SAVMs.
Methods
In this study, 91 consecutive patients with SAVM between January 1993 and November 2014 were evaluated. Initial clinical presentations, radiological findings, treatment results, and follow-up outcomes were evaluated according to disease type and treatment modalities. Patient status was scored using the modified Rankin scale (mRS) and Aminoff–Logue Disability scale (ALS).
Results
Of the SAVM patients 69 % were male and 31 % were female with a mean age of 49 years (range 11–82 years). At the time of initial imaging evaluation, myelopathy was the most common finding with main complaints of gait disturbance (69 out of 91, 76 %), sensory disturbances (61/91, 67 %), and bowel or bladder symptoms (51/91, 56 %). Among the 80 patients who received treatment 56 (62 %) underwent endovascular embolization and 24 (26 %) underwent surgery. Complete obliteration was achieved in 47 patients (84 %) after endovascular embolization and in 18 (75 %) after surgical ligation. At the time of final follow-up 67 patients (84 %) showed improvement of more than 1 point on the mRS, while 69 (86 %) showed significant improvement on the ALS after treatment.
Conclusion
The SAVMs presented with diverse neurological deficits, including myelopathy. Endovascular or surgical treatment of SAVMs can result in good clinical outcomes in most patients.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Arteriovenous malformations</subject><subject>Arteriovenous Malformations - diagnosis</subject><subject>Arteriovenous Malformations - pathology</subject><subject>Arteriovenous Malformations - therapy</subject><subject>Care and treatment</subject><subject>Central Nervous System Vascular Malformations - diagnosis</subject><subject>Central Nervous System Vascular Malformations - pathology</subject><subject>Central Nervous System Vascular Malformations - therapy</subject><subject>Child</subject><subject>Clinical outcomes</subject><subject>Embolization, Therapeutic</subject><subject>Female</subject><subject>Homeopathy</subject><subject>Humans</subject><subject>Male</subject><subject>Materia medica and therapeutics</subject><subject>Medical colleges</subject><subject>Medical research</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Medicine, Experimental</subject><subject>Middle Aged</subject><subject>Neurology</subject><subject>Neuroradiology</subject><subject>Neurosurgery</subject><subject>Original Article</subject><subject>Patient outcomes</subject><subject>Retrospective Studies</subject><subject>Therapeutics</subject><subject>Treatment Outcome</subject><subject>Young Adult</subject><issn>1869-1439</issn><issn>1869-1447</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kU9LHTEUxUOpVHn6AdyUgW66Gc3N_MnM8vFotWBxoa5DJnNjIzPJa5IR_Pa9j2eVSiWLhOR3DufmMHYK_Aw4l-eJc96KkkNb8qaGkn9gR9C1fQl1LT--nKv-kJ2k9EA0r7q-aeQndihkK4So5RG720zOO6OnYvNLR20yRpeyM6nQfixuI-o8o8_F9ZJNmDEVwRY3W-dJsI47ODyiD0sqfurJhjjr7IJPx-zA6inhyfO-Ynffv91uLsur64sfm_VVaShXLrt2RKG15tb2ph1oa-wAFaAdBSVtTAfQCisGHMZ6wNYAdHIQllg7jravVuzr3ncbw-8FU1azSwanSXukUAq6ppdQkw2hX96gD2GJNEdSgvNO9ryq5Ct1rydUztuQ6VN2pmotoRMSRC-IOvsPRWvE2Zng0Tq6_0cAe4GJIaWIVm2jm3V8UsDVrk21b1NRm2rXpuKk-fwceBlmHF8Uf7sjQOyBRE_-HuPrRO-7_gFgfKmE</recordid><startdate>20180301</startdate><enddate>20180301</enddate><creator>Park, Ji Eun</creator><creator>Koo, Hae-Won</creator><creator>Liu, Hairi</creator><creator>Jung, Seung Chul</creator><creator>Park, Danbi</creator><creator>Suh, Dae Chul</creator><general>Springer Berlin Heidelberg</general><general>Springer</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20180301</creationdate><title>Clinical Characteristics and Treatment Outcomes of Spinal Arteriovenous Malformations</title><author>Park, Ji Eun ; Koo, Hae-Won ; Liu, Hairi ; Jung, Seung Chul ; Park, Danbi ; Suh, Dae Chul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c439t-86de2aaa0ff9c6b0ff5fb131efd29555c81162f2bebd4be6c1187b2fc6bfddf93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Arteriovenous malformations</topic><topic>Arteriovenous Malformations - diagnosis</topic><topic>Arteriovenous Malformations - pathology</topic><topic>Arteriovenous Malformations - therapy</topic><topic>Care and treatment</topic><topic>Central Nervous System Vascular Malformations - diagnosis</topic><topic>Central Nervous System Vascular Malformations - pathology</topic><topic>Central Nervous System Vascular Malformations - therapy</topic><topic>Child</topic><topic>Clinical outcomes</topic><topic>Embolization, Therapeutic</topic><topic>Female</topic><topic>Homeopathy</topic><topic>Humans</topic><topic>Male</topic><topic>Materia medica and therapeutics</topic><topic>Medical colleges</topic><topic>Medical research</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Medicine, Experimental</topic><topic>Middle Aged</topic><topic>Neurology</topic><topic>Neuroradiology</topic><topic>Neurosurgery</topic><topic>Original Article</topic><topic>Patient outcomes</topic><topic>Retrospective Studies</topic><topic>Therapeutics</topic><topic>Treatment Outcome</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Park, Ji Eun</creatorcontrib><creatorcontrib>Koo, Hae-Won</creatorcontrib><creatorcontrib>Liu, Hairi</creatorcontrib><creatorcontrib>Jung, Seung Chul</creatorcontrib><creatorcontrib>Park, Danbi</creatorcontrib><creatorcontrib>Suh, Dae Chul</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical neuroradiology (Munich)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Park, Ji Eun</au><au>Koo, Hae-Won</au><au>Liu, Hairi</au><au>Jung, Seung Chul</au><au>Park, Danbi</au><au>Suh, Dae Chul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical Characteristics and Treatment Outcomes of Spinal Arteriovenous Malformations</atitle><jtitle>Clinical neuroradiology (Munich)</jtitle><stitle>Clin Neuroradiol</stitle><addtitle>Clin Neuroradiol</addtitle><date>2018-03-01</date><risdate>2018</risdate><volume>28</volume><issue>1</issue><spage>39</spage><epage>46</epage><pages>39-46</pages><issn>1869-1439</issn><eissn>1869-1447</eissn><abstract>Purpose
Spinal arteriovenous malformations (SAVMs) are rare events. This study evaluated initial clinical presentations and treatment outcomes of SAVMs.
Methods
In this study, 91 consecutive patients with SAVM between January 1993 and November 2014 were evaluated. Initial clinical presentations, radiological findings, treatment results, and follow-up outcomes were evaluated according to disease type and treatment modalities. Patient status was scored using the modified Rankin scale (mRS) and Aminoff–Logue Disability scale (ALS).
Results
Of the SAVM patients 69 % were male and 31 % were female with a mean age of 49 years (range 11–82 years). At the time of initial imaging evaluation, myelopathy was the most common finding with main complaints of gait disturbance (69 out of 91, 76 %), sensory disturbances (61/91, 67 %), and bowel or bladder symptoms (51/91, 56 %). Among the 80 patients who received treatment 56 (62 %) underwent endovascular embolization and 24 (26 %) underwent surgery. Complete obliteration was achieved in 47 patients (84 %) after endovascular embolization and in 18 (75 %) after surgical ligation. At the time of final follow-up 67 patients (84 %) showed improvement of more than 1 point on the mRS, while 69 (86 %) showed significant improvement on the ALS after treatment.
Conclusion
The SAVMs presented with diverse neurological deficits, including myelopathy. Endovascular or surgical treatment of SAVMs can result in good clinical outcomes in most patients.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>27622247</pmid><doi>10.1007/s00062-016-0541-0</doi><tpages>8</tpages></addata></record> |
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| subjects | Adolescent Adult Aged Aged, 80 and over Arteriovenous malformations Arteriovenous Malformations - diagnosis Arteriovenous Malformations - pathology Arteriovenous Malformations - therapy Care and treatment Central Nervous System Vascular Malformations - diagnosis Central Nervous System Vascular Malformations - pathology Central Nervous System Vascular Malformations - therapy Child Clinical outcomes Embolization, Therapeutic Female Homeopathy Humans Male Materia medica and therapeutics Medical colleges Medical research Medicine Medicine & Public Health Medicine, Experimental Middle Aged Neurology Neuroradiology Neurosurgery Original Article Patient outcomes Retrospective Studies Therapeutics Treatment Outcome Young Adult |
| title | Clinical Characteristics and Treatment Outcomes of Spinal Arteriovenous Malformations |
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