FOXO3a Expression Regulated by ERK Signaling is Inversely Correlated With Y‐Box Binding Protein‐1 Expression in Prostate Cancer

BACKGROUND FOXO3a is a member of the forkhead O transcription factors. FOXO3a induces the factors that contribute to cell cycle arrest and is considered a tumor suppressor in several malignant tumors. Y‐box binding protein‐1 (YB‐1) is a multifunctional protein whose high expression is correlated wit...

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Veröffentlicht in:	The Prostate 2017-02, Vol.77 (2), p.145-153
Hauptverfasser:	Imada, Kenjiro, Shiota, Masaki, Kuroiwa, Kentaro, Sugimoto, Masaaki, Abe, Tatsuro, Kohashi, Kenichi, Yokomizo, Akira, Eto, Masatoshi, Naito, Seiji, Oda, Yoshinao
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Cell activation Cell cycle Cell Line, Tumor Cytotoxicity ERK Forkhead Box Protein O3 - biosynthesis Forkhead Box Protein O3 - genetics Forkhead protein FOXO3 protein FOXO3a Gene Expression Regulation, Neoplastic Humans Male MAP Kinase Signaling System - physiology Metformin Middle Aged Phosphorylation - physiology Prostate cancer Prostatectomy Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Proteins Transcription factors Tumor suppressor genes Tumors Western blotting Y-Box-Binding Protein 1 - biosynthesis Y-Box-Binding Protein 1 - genetics YB‐1
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