Excretion rates of indigestible plastic balls of different specific gravities and diameters in dairy cattle

We used plastic balls to investigate how their specific gravity and diameter affect excretion rate and rumination in dairy cattle, to develop a capsule that can be used for reaching the lower gastrointestinal tract without physical breakdown and/or degradation in the rumen. Twelve types of indigesti...

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Veröffentlicht in:Animal science journal 2017-01, Vol.88 (1), p.94-98
Hauptverfasser: Seyama, Tomohiro, Hirayasu, Hirofumi, Kasai, Koji
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container_title Animal science journal
container_volume 88
creator Seyama, Tomohiro
Hirayasu, Hirofumi
Kasai, Koji
description We used plastic balls to investigate how their specific gravity and diameter affect excretion rate and rumination in dairy cattle, to develop a capsule that can be used for reaching the lower gastrointestinal tract without physical breakdown and/or degradation in the rumen. Twelve types of indigestible plastic balls composed of a combination of four specific gravities (0.95, 1.19, 1.41, or 2.20) and three diameters (3.97, 6.35, or 7.94 mm) were orally administered to lactating dairy cows, and the balls were collected from feces, after 120 h post‐administration, to evaluate the recovery rate. Recovery rate of the balls with specific gravity 1.19 or 1.41 and diameter 6.35 or 7.94 mm was higher than those with specific gravity 0.95 or 2.20 and diameter 3.97 mm. The cumulative recovery rate at 24 and 48 h post‐administration was higher for balls with specific gravity 1.19 than that for balls with other specific gravities. These results suggest that specific gravity 1.19 or 1.41 and diameters 6.35−7.94 mm are optimal for use in bypass capsules for administration to cattle. In addition, the passage time of capsules differed between specific gravities 1.19 and 1.41.
doi_str_mv 10.1111/asj.12590
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source MEDLINE; Wiley Online Library Journals Frontfile Complete; Alma/SFX Local Collection
subjects Administration, Oral
Animal Nutritional Physiological Phenomena
Animals
Biological Transport
Capsules - administration & dosage
Capsules - pharmacokinetics
Cattle
Cattle - physiology
dairy cattle
Drug Delivery Systems
excretion rate
Female
Food
Gravity
Intestinal Elimination - physiology
Lactation
Particle Size
Plastics
Rumen - physiology
rumen bypass
Specific Gravity
specific gravity and diameter
Time Factors
title Excretion rates of indigestible plastic balls of different specific gravities and diameters in dairy cattle
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