Resveratrol Pretreatment Decreases Ischemic Injury and Improves Neurological Function Via Sonic Hedgehog Signaling After Stroke in Rats

Resveratrol has neuroprotective effects for ischemic cerebral stroke. However, its neuroprotective mechanism for stroke is less well understood. Beneficial actions of the activated Sonic hedgehog (Shh) signaling pathway in stroke, such as improving neurological function, promoting neurogenesis, anti...

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Veröffentlicht in:	Molecular neurobiology 2017-01, Vol.54 (1), p.212-226
Hauptverfasser:	Yu, Pingping, Wang, Li, Tang, Fanren, Zeng, Li, Zhou, Luling, Song, Xiaosong, Jia, Wei, Chen, Jixiang, Yang, Qin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Antioxidants - administration & dosage Biomedical and Life Sciences Biomedicine Brain Ischemia - drug therapy Brain Ischemia - metabolism Brain Ischemia - pathology Cell Biology Drug therapy Female Hedgehog Proteins - biosynthesis Ischemia Male Neurobiology Neurology Neuroprotective Agents - administration & dosage Neurosciences Rats Rats, Sprague-Dawley Recovery of Function - drug effects Recovery of Function - physiology Resveratrol Rodents Signal Transduction - drug effects Signal Transduction - physiology Stilbenes - administration & dosage Stroke Stroke - drug therapy Stroke - metabolism Stroke - pathology Treatment Outcome
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