Cytotoxicity of Endogenous Lipids N-acyl Dopamines and their Possible Metabolic Derivatives for Human Cancer Cell Lines of Different Histological Origin

Dopamine amides of long chain fatty acids are a family of endogenous mammalian lipids with an unknown function; they are anti-proliferative for the C6 glioblastoma cell line. To assess their possible anti-cancer activity we evaluated their cytotoxicity for a set of cancer cell lines. Anti-proliferat...

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Veröffentlicht in:	Anticancer research 2015-05, Vol.35 (5), p.2657-2661
Hauptverfasser:	Akimov, Mikhail G, Gretskaya, Natalia M, Zinchenko, Galina N, Bezuglov, Vladimir V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dopamine - analogs & derivatives Dopamine - metabolism Fatty Acids - metabolism Glioblastoma - metabolism Glioblastoma - pathology HEK293 Cells Humans Lipids MCF-7 Cells Neoplasms - metabolism Neoplasms - pathology Structure-Activity Relationship
Online-Zugang:	Volltext
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