Lack of tumor necrosis factor alpha gene polymorphism -857c/t (rs1799724) association in Pakistani rheumatoid arthritis patients

Background Rheumatoid arthritis (RA) is a common systemic autoimmune disease, influenced greatly by the pro‐inflammatory cytokine tumor necrosis factor‐ alpha (TNF‐α). Single nucleotide polymorphisms (SNPs) in regulatory regions of the TNF‐α gene play a significant role in disease development and pa...

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Veröffentlicht in:	International journal of rheumatic diseases 2016-11, Vol.19 (11), p.1119-1125
Hauptverfasser:	Sadaf, Tayyaba, John, Peter, Bhatti, Attya, Jahangir, Sidrah, Kiani, Aysha K., Gill, Farah A., Malik, Javed M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Analysis of Variance Arthritis, Rheumatoid - diagnosis Arthritis, Rheumatoid - genetics Arthritis, Rheumatoid - immunology association Case-Control Studies Chi-Square Distribution Female Gangrene Gene Frequency Genes Genetic Association Studies Genetic Predisposition to Disease Humans Male Middle Aged Odds Ratio Pakistan Phenotype polymorphism Polymorphism, Single Nucleotide Rheumatoid arthritis Risk Factors Severity of Illness Index tumor necrosis factor alpha Tumor Necrosis Factor-alpha - genetics Tumor necrosis factor-TNF
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