Contraction mode and whey protein intake affect the synthesis rate of intramuscular connective tissue
ABSTRACT Introduction In this study we investigated the impact of whey protein hydrolysate and maltodextrin (WPH) intake on intramuscular connective tissue (IMCT) protein fractional synthesis rate (FSR) after maximal shortening and lengthening contractions. Methods Twenty young men were randomized t...
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| Veröffentlicht in: | Muscle & nerve 2017-01, Vol.55 (1), p.128-130 |
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| creator | Holm, Lars Rahbek, Stine Klejs Farup, Jean Vendelbo, Mikkel Holm Vissing, Kristian |
| description | ABSTRACT
Introduction
In this study we investigated the impact of whey protein hydrolysate and maltodextrin (WPH) intake on intramuscular connective tissue (IMCT) protein fractional synthesis rate (FSR) after maximal shortening and lengthening contractions.
Methods
Twenty young men were randomized to receive either WPH or maltodextrin [carbohydrate (CHO)] immediately after completion of unilateral shortening and lengthening knee extensions. Ring‐13C6‐phenylalanine was infused, and muscle biopsies were obtained. IMCT protein FSR was measured at 1–5, as well as 1–3 and 3–5 hours after contractions and nutrient intake.
Results
During the 1–3‐hour recovery, lengthening contractions resulted in a higher FSR than shortening contractions (P |
| doi_str_mv | 10.1002/mus.25398 |
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Introduction
In this study we investigated the impact of whey protein hydrolysate and maltodextrin (WPH) intake on intramuscular connective tissue (IMCT) protein fractional synthesis rate (FSR) after maximal shortening and lengthening contractions.
Methods
Twenty young men were randomized to receive either WPH or maltodextrin [carbohydrate (CHO)] immediately after completion of unilateral shortening and lengthening knee extensions. Ring‐13C6‐phenylalanine was infused, and muscle biopsies were obtained. IMCT protein FSR was measured at 1–5, as well as 1–3 and 3–5 hours after contractions and nutrient intake.
Results
During the 1–3‐hour recovery, lengthening contractions resulted in a higher FSR than shortening contractions (P < 0.01), independent of supplementation type and, during the 3–5‐hour recovery, WPH had a higher FSR than CHO (P < 0.05), independent of prior contraction mode.
Conclusions
The later appearance of a stimulating effect of WPH on the IMCT FSR after strenuous muscle contractions lends support to its ability to promote recovery of the muscle connective tissue matrix after exercise. Muscle Nerve 55: 128–130, 2017</description><identifier>ISSN: 0148-639X</identifier><identifier>EISSN: 1097-4598</identifier><identifier>DOI: 10.1002/mus.25398</identifier><identifier>PMID: 27603578</identifier><identifier>CODEN: MUNEDE</identifier><language>eng</language><publisher>United States: Wiley Subscription Services, Inc</publisher><subject>Adult ; Analysis of Variance ; Carbohydrates ; concentric contraction ; Connective Tissue - drug effects ; Connective Tissue - metabolism ; Connective tissues ; eccentric contraction ; Food intake ; fractional synthesis rate ; Functional Laterality ; Humans ; Male ; Maltodextrin ; milk protein ; muscle collagen ; Muscle contraction ; Muscle Contraction - physiology ; Muscle Proteins - metabolism ; Muscle, Skeletal - cytology ; Muscles ; Muscular function ; Phenylalanine ; Polysaccharides - pharmacology ; Protein biosynthesis ; Proteins ; Recovery ; resistance exercise ; Supplements ; Synthesis ; Tissues ; Whey ; Whey protein ; Whey Proteins - biosynthesis ; Whey Proteins - metabolism ; Young Adult</subject><ispartof>Muscle & nerve, 2017-01, Vol.55 (1), p.128-130</ispartof><rights>2016 Wiley Periodicals, Inc.</rights><rights>2017 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4148-2d238c34fb8db42b5e6cb73e2aafaed1244654050b2ca692cffc5a3bda77c50b3</citedby><cites>FETCH-LOGICAL-c4148-2d238c34fb8db42b5e6cb73e2aafaed1244654050b2ca692cffc5a3bda77c50b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fmus.25398$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fmus.25398$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,777,781,1412,27905,27906,45555,45556</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27603578$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Holm, Lars</creatorcontrib><creatorcontrib>Rahbek, Stine Klejs</creatorcontrib><creatorcontrib>Farup, Jean</creatorcontrib><creatorcontrib>Vendelbo, Mikkel Holm</creatorcontrib><creatorcontrib>Vissing, Kristian</creatorcontrib><title>Contraction mode and whey protein intake affect the synthesis rate of intramuscular connective tissue</title><title>Muscle & nerve</title><addtitle>Muscle Nerve</addtitle><description>ABSTRACT
Introduction
In this study we investigated the impact of whey protein hydrolysate and maltodextrin (WPH) intake on intramuscular connective tissue (IMCT) protein fractional synthesis rate (FSR) after maximal shortening and lengthening contractions.
Methods
Twenty young men were randomized to receive either WPH or maltodextrin [carbohydrate (CHO)] immediately after completion of unilateral shortening and lengthening knee extensions. Ring‐13C6‐phenylalanine was infused, and muscle biopsies were obtained. IMCT protein FSR was measured at 1–5, as well as 1–3 and 3–5 hours after contractions and nutrient intake.
Results
During the 1–3‐hour recovery, lengthening contractions resulted in a higher FSR than shortening contractions (P < 0.01), independent of supplementation type and, during the 3–5‐hour recovery, WPH had a higher FSR than CHO (P < 0.05), independent of prior contraction mode.
Conclusions
The later appearance of a stimulating effect of WPH on the IMCT FSR after strenuous muscle contractions lends support to its ability to promote recovery of the muscle connective tissue matrix after exercise. Muscle Nerve 55: 128–130, 2017</description><subject>Adult</subject><subject>Analysis of Variance</subject><subject>Carbohydrates</subject><subject>concentric contraction</subject><subject>Connective Tissue - drug effects</subject><subject>Connective Tissue - metabolism</subject><subject>Connective tissues</subject><subject>eccentric contraction</subject><subject>Food intake</subject><subject>fractional synthesis rate</subject><subject>Functional Laterality</subject><subject>Humans</subject><subject>Male</subject><subject>Maltodextrin</subject><subject>milk protein</subject><subject>muscle collagen</subject><subject>Muscle contraction</subject><subject>Muscle Contraction - physiology</subject><subject>Muscle Proteins - metabolism</subject><subject>Muscle, Skeletal - cytology</subject><subject>Muscles</subject><subject>Muscular function</subject><subject>Phenylalanine</subject><subject>Polysaccharides - pharmacology</subject><subject>Protein biosynthesis</subject><subject>Proteins</subject><subject>Recovery</subject><subject>resistance exercise</subject><subject>Supplements</subject><subject>Synthesis</subject><subject>Tissues</subject><subject>Whey</subject><subject>Whey protein</subject><subject>Whey Proteins - biosynthesis</subject><subject>Whey Proteins - metabolism</subject><subject>Young Adult</subject><issn>0148-639X</issn><issn>1097-4598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqN0U2LFDEQBuAgijuuHvwDEvCih9nNZyc5yuAXrHjQBW8hna6wWbuTNUm7zL8346weBMVTQfHwplKF0FNKzigh7HxZ6xmT3Oh7aEOJUVshjb6PNoQKvR24-XKCHtV6TQihelAP0QlTA-FS6Q2CXU6tON9iTnjJE2CXJnx7BXt8U3KDmHBMzX3t_RDAN9yuANd96qXGiotrgHM4mOL6GH6dXcE-p9Rt_A64xVpXeIweBDdXeHJXT9Hlm9efd--2Fx_fvt-9uth6cRiVTYxrz0UY9TQKNkoY_Kg4MOeCg4kyIQYpiCQj824wzIfgpePj5JTyvctP0Ytjbp_92wq12SVWD_PsEuS1WqqlEYppqv-DcsmVYfJAn_9Br_NaUv-IZVwSagwT7F-qP0uYGCiRXb08Kl9yrQWCvSlxcWVvKbGHY9q-RfvzmN0-u0tcxwWm3_LX9To4P4LbOMP-70n2w-WnY-QP3dOpcA</recordid><startdate>201701</startdate><enddate>201701</enddate><creator>Holm, Lars</creator><creator>Rahbek, Stine Klejs</creator><creator>Farup, Jean</creator><creator>Vendelbo, Mikkel Holm</creator><creator>Vissing, Kristian</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7TS</scope><scope>7U7</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>201701</creationdate><title>Contraction mode and whey protein intake affect the synthesis rate of intramuscular connective tissue</title><author>Holm, Lars ; Rahbek, Stine Klejs ; Farup, Jean ; Vendelbo, Mikkel Holm ; Vissing, Kristian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4148-2d238c34fb8db42b5e6cb73e2aafaed1244654050b2ca692cffc5a3bda77c50b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Analysis of Variance</topic><topic>Carbohydrates</topic><topic>concentric contraction</topic><topic>Connective Tissue - drug effects</topic><topic>Connective Tissue - metabolism</topic><topic>Connective tissues</topic><topic>eccentric contraction</topic><topic>Food intake</topic><topic>fractional synthesis rate</topic><topic>Functional Laterality</topic><topic>Humans</topic><topic>Male</topic><topic>Maltodextrin</topic><topic>milk protein</topic><topic>muscle collagen</topic><topic>Muscle contraction</topic><topic>Muscle Contraction - physiology</topic><topic>Muscle Proteins - metabolism</topic><topic>Muscle, Skeletal - cytology</topic><topic>Muscles</topic><topic>Muscular function</topic><topic>Phenylalanine</topic><topic>Polysaccharides - pharmacology</topic><topic>Protein biosynthesis</topic><topic>Proteins</topic><topic>Recovery</topic><topic>resistance exercise</topic><topic>Supplements</topic><topic>Synthesis</topic><topic>Tissues</topic><topic>Whey</topic><topic>Whey protein</topic><topic>Whey Proteins - biosynthesis</topic><topic>Whey Proteins - metabolism</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Holm, Lars</creatorcontrib><creatorcontrib>Rahbek, Stine Klejs</creatorcontrib><creatorcontrib>Farup, Jean</creatorcontrib><creatorcontrib>Vendelbo, Mikkel Holm</creatorcontrib><creatorcontrib>Vissing, Kristian</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Physical Education Index</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>Muscle & nerve</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Holm, Lars</au><au>Rahbek, Stine Klejs</au><au>Farup, Jean</au><au>Vendelbo, Mikkel Holm</au><au>Vissing, Kristian</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Contraction mode and whey protein intake affect the synthesis rate of intramuscular connective tissue</atitle><jtitle>Muscle & nerve</jtitle><addtitle>Muscle Nerve</addtitle><date>2017-01</date><risdate>2017</risdate><volume>55</volume><issue>1</issue><spage>128</spage><epage>130</epage><pages>128-130</pages><issn>0148-639X</issn><eissn>1097-4598</eissn><coden>MUNEDE</coden><abstract>ABSTRACT
Introduction
In this study we investigated the impact of whey protein hydrolysate and maltodextrin (WPH) intake on intramuscular connective tissue (IMCT) protein fractional synthesis rate (FSR) after maximal shortening and lengthening contractions.
Methods
Twenty young men were randomized to receive either WPH or maltodextrin [carbohydrate (CHO)] immediately after completion of unilateral shortening and lengthening knee extensions. Ring‐13C6‐phenylalanine was infused, and muscle biopsies were obtained. IMCT protein FSR was measured at 1–5, as well as 1–3 and 3–5 hours after contractions and nutrient intake.
Results
During the 1–3‐hour recovery, lengthening contractions resulted in a higher FSR than shortening contractions (P < 0.01), independent of supplementation type and, during the 3–5‐hour recovery, WPH had a higher FSR than CHO (P < 0.05), independent of prior contraction mode.
Conclusions
The later appearance of a stimulating effect of WPH on the IMCT FSR after strenuous muscle contractions lends support to its ability to promote recovery of the muscle connective tissue matrix after exercise. Muscle Nerve 55: 128–130, 2017</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>27603578</pmid><doi>10.1002/mus.25398</doi><tpages>3</tpages></addata></record> |
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| subjects | Adult Analysis of Variance Carbohydrates concentric contraction Connective Tissue - drug effects Connective Tissue - metabolism Connective tissues eccentric contraction Food intake fractional synthesis rate Functional Laterality Humans Male Maltodextrin milk protein muscle collagen Muscle contraction Muscle Contraction - physiology Muscle Proteins - metabolism Muscle, Skeletal - cytology Muscles Muscular function Phenylalanine Polysaccharides - pharmacology Protein biosynthesis Proteins Recovery resistance exercise Supplements Synthesis Tissues Whey Whey protein Whey Proteins - biosynthesis Whey Proteins - metabolism Young Adult |
| title | Contraction mode and whey protein intake affect the synthesis rate of intramuscular connective tissue |
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