4 β ‐Hydroxycholesterol Level in Patients With Rheumatoid Arthritis Before vs. After Initiation of bDMARDs and Correlation With Inflammatory State

Systemic inflammation has been linked to suppressed CYP3A(4) activity. We determined 4 β ‐hydroxycholesterol (4 β OHC), an endogenous CYP3A4 metabolite, in patients with rheumatoid arthritis (RA) before and after treatment with biological disease‐modifying antirheumatic drugs (bDMARDs). The 4 β OHC...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Clinical and translational science 2017-01, Vol.10 (1), p.42-49
Hauptverfasser:	Wollmann, B M, Syversen, S W, Lie, E, Gjestad, C, Mehus, L L, Olsen, I C, Molden, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Cytokines Disease Drug dosages Enzymes Erythrocyte sedimentation rate Erythrocytes Genotype & phenotype Glycoproteins Inflammation Inflammatory diseases Inhibitors Lymphocytes B Medical treatment Metabolism Metabolites Phenotypes Rheumatoid arthritis Studies Tumor necrosis factor-α
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!