Effects of labetalol on hemodynamics and seizure duration during ECT

Effects of labetalol on hemodynamics and seizure duration during ECT

Beta blockers are commonly used to attenuate the transient increase in heart rate (HR) and blood pressure (BP) that accompany electroconvulsive therapy (ECT). Recent reports have suggested that several beta blockers have anticonvulsant properties and hence could be countertherapeutic with ECT. In a...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Convulsive therapy 1991, Vol.7 (1), p.5-14
Hauptverfasser: VAUGHN MCCALL, W, SHELP, F. E, WEINER, R. D, AUSTIN, S, HARRILL, A
Format: Artikel
Sprache:eng
Schlagworte:
Biological and medical sciences
Catecholaminergic system
Medical sciences
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 14
container_issue 1
container_start_page 5
container_title Convulsive therapy
container_volume 7
creator VAUGHN MCCALL, W
SHELP, F. E
WEINER, R. D
AUSTIN, S
HARRILL, A
description Beta blockers are commonly used to attenuate the transient increase in heart rate (HR) and blood pressure (BP) that accompany electroconvulsive therapy (ECT). Recent reports have suggested that several beta blockers have anticonvulsant properties and hence could be countertherapeutic with ECT. In a randomized, double-blind controlled study of the dose response effects of intravenous labetalol on ECT hemodynamics and seizure duration, labetalol exhibited dose-dependent reduction in HR and rate pressure product (RPP) at the 5 and 10 mg doses compared to placebo. However, no significant differences between labetalol 5 mg, 10 mg, or placebo were found on BP or seizure duration.
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1859371301</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1859371301</sourcerecordid><originalsourceid>FETCH-LOGICAL-p239t-bc297b148614eaf910224d9345ee4559ccd2cadd381c98e88e08f0e2e0d0ea493</originalsourceid><addsrcrecordid>eNpFz0tLAzEUBeAgiq3VvyDZCG4G8nRyl1LrAwpu6nq4k9xoZB51MrOov94BK67OWXwcOCdsqXRpCrDgTtlSlAYKJ6xdsIucP4WwWgKcs4WUYKQAsWQPmxjJj5n3kTdY04hN3_C-4x_U9uHQYZt85tgFnil9TwPxMA04plnMJXXvfLPeXbKziE2mq2Ou2NvjZrd-LravTy_r-22xVxrGovYKyloadycNYQQplDIBtLFExlrwPiiPIWgnPThyjoSLghSJIAgN6BW7_d3dD_3XRHms2pQ9NQ121E-5ks6CLqUWcqbXRzrVLYVqP6QWh0P193wGN0eA2WMTB-x8yv8OrLGgnP4BI1FiDA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1859371301</pqid></control><display><type>article</type><title>Effects of labetalol on hemodynamics and seizure duration during ECT</title><source>Journals@Ovid Complete</source><creator>VAUGHN MCCALL, W ; SHELP, F. E ; WEINER, R. D ; AUSTIN, S ; HARRILL, A</creator><creatorcontrib>VAUGHN MCCALL, W ; SHELP, F. E ; WEINER, R. D ; AUSTIN, S ; HARRILL, A</creatorcontrib><description>Beta blockers are commonly used to attenuate the transient increase in heart rate (HR) and blood pressure (BP) that accompany electroconvulsive therapy (ECT). Recent reports have suggested that several beta blockers have anticonvulsant properties and hence could be countertherapeutic with ECT. In a randomized, double-blind controlled study of the dose response effects of intravenous labetalol on ECT hemodynamics and seizure duration, labetalol exhibited dose-dependent reduction in HR and rate pressure product (RPP) at the 5 and 10 mg doses compared to placebo. However, no significant differences between labetalol 5 mg, 10 mg, or placebo were found on BP or seizure duration.</description><identifier>ISSN: 0749-8055</identifier><identifier>EISSN: 2374-9598</identifier><identifier>PMID: 11941090</identifier><identifier>CODEN: COTHE4</identifier><language>eng</language><publisher>New York, NY: Raven Press</publisher><subject>Biological and medical sciences ; Catecholaminergic system ; Medical sciences ; Neuropharmacology ; Neurotransmitters. Neurotransmission. Receptors ; Pharmacology. Drug treatments</subject><ispartof>Convulsive therapy, 1991, Vol.7 (1), p.5-14</ispartof><rights>1991 INIST-CNRS</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4024</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=19545928$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11941090$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>VAUGHN MCCALL, W</creatorcontrib><creatorcontrib>SHELP, F. E</creatorcontrib><creatorcontrib>WEINER, R. D</creatorcontrib><creatorcontrib>AUSTIN, S</creatorcontrib><creatorcontrib>HARRILL, A</creatorcontrib><title>Effects of labetalol on hemodynamics and seizure duration during ECT</title><title>Convulsive therapy</title><addtitle>Convuls Ther</addtitle><description>Beta blockers are commonly used to attenuate the transient increase in heart rate (HR) and blood pressure (BP) that accompany electroconvulsive therapy (ECT). Recent reports have suggested that several beta blockers have anticonvulsant properties and hence could be countertherapeutic with ECT. In a randomized, double-blind controlled study of the dose response effects of intravenous labetalol on ECT hemodynamics and seizure duration, labetalol exhibited dose-dependent reduction in HR and rate pressure product (RPP) at the 5 and 10 mg doses compared to placebo. However, no significant differences between labetalol 5 mg, 10 mg, or placebo were found on BP or seizure duration.</description><subject>Biological and medical sciences</subject><subject>Catecholaminergic system</subject><subject>Medical sciences</subject><subject>Neuropharmacology</subject><subject>Neurotransmitters. Neurotransmission. Receptors</subject><subject>Pharmacology. Drug treatments</subject><issn>0749-8055</issn><issn>2374-9598</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><recordid>eNpFz0tLAzEUBeAgiq3VvyDZCG4G8nRyl1LrAwpu6nq4k9xoZB51MrOov94BK67OWXwcOCdsqXRpCrDgTtlSlAYKJ6xdsIucP4WwWgKcs4WUYKQAsWQPmxjJj5n3kTdY04hN3_C-4x_U9uHQYZt85tgFnil9TwPxMA04plnMJXXvfLPeXbKziE2mq2Ou2NvjZrd-LravTy_r-22xVxrGovYKyloadycNYQQplDIBtLFExlrwPiiPIWgnPThyjoSLghSJIAgN6BW7_d3dD_3XRHms2pQ9NQ121E-5ks6CLqUWcqbXRzrVLYVqP6QWh0P193wGN0eA2WMTB-x8yv8OrLGgnP4BI1FiDA</recordid><startdate>1991</startdate><enddate>1991</enddate><creator>VAUGHN MCCALL, W</creator><creator>SHELP, F. E</creator><creator>WEINER, R. D</creator><creator>AUSTIN, S</creator><creator>HARRILL, A</creator><general>Raven Press</general><scope>IQODW</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>1991</creationdate><title>Effects of labetalol on hemodynamics and seizure duration during ECT</title><author>VAUGHN MCCALL, W ; SHELP, F. E ; WEINER, R. D ; AUSTIN, S ; HARRILL, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p239t-bc297b148614eaf910224d9345ee4559ccd2cadd381c98e88e08f0e2e0d0ea493</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Biological and medical sciences</topic><topic>Catecholaminergic system</topic><topic>Medical sciences</topic><topic>Neuropharmacology</topic><topic>Neurotransmitters. Neurotransmission. Receptors</topic><topic>Pharmacology. Drug treatments</topic><toplevel>online_resources</toplevel><creatorcontrib>VAUGHN MCCALL, W</creatorcontrib><creatorcontrib>SHELP, F. E</creatorcontrib><creatorcontrib>WEINER, R. D</creatorcontrib><creatorcontrib>AUSTIN, S</creatorcontrib><creatorcontrib>HARRILL, A</creatorcontrib><collection>Pascal-Francis</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Convulsive therapy</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>VAUGHN MCCALL, W</au><au>SHELP, F. E</au><au>WEINER, R. D</au><au>AUSTIN, S</au><au>HARRILL, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effects of labetalol on hemodynamics and seizure duration during ECT</atitle><jtitle>Convulsive therapy</jtitle><addtitle>Convuls Ther</addtitle><date>1991</date><risdate>1991</risdate><volume>7</volume><issue>1</issue><spage>5</spage><epage>14</epage><pages>5-14</pages><issn>0749-8055</issn><eissn>2374-9598</eissn><coden>COTHE4</coden><abstract>Beta blockers are commonly used to attenuate the transient increase in heart rate (HR) and blood pressure (BP) that accompany electroconvulsive therapy (ECT). Recent reports have suggested that several beta blockers have anticonvulsant properties and hence could be countertherapeutic with ECT. In a randomized, double-blind controlled study of the dose response effects of intravenous labetalol on ECT hemodynamics and seizure duration, labetalol exhibited dose-dependent reduction in HR and rate pressure product (RPP) at the 5 and 10 mg doses compared to placebo. However, no significant differences between labetalol 5 mg, 10 mg, or placebo were found on BP or seizure duration.</abstract><cop>New York, NY</cop><pub>Raven Press</pub><pmid>11941090</pmid><tpages>10</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0749-8055
ispartof Convulsive therapy, 1991, Vol.7 (1), p.5-14
issn 0749-8055
2374-9598
language eng
recordid cdi_proquest_miscellaneous_1859371301
source Journals@Ovid Complete
subjects Biological and medical sciences
Catecholaminergic system
Medical sciences
Neuropharmacology
Neurotransmitters. Neurotransmission. Receptors
Pharmacology. Drug treatments
title Effects of labetalol on hemodynamics and seizure duration during ECT
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-02T21%3A31%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Effects%20of%20labetalol%20on%20hemodynamics%20and%20seizure%20duration%20during%20ECT&rft.jtitle=Convulsive%20therapy&rft.au=VAUGHN%20MCCALL,%20W&rft.date=1991&rft.volume=7&rft.issue=1&rft.spage=5&rft.epage=14&rft.pages=5-14&rft.issn=0749-8055&rft.eissn=2374-9598&rft.coden=COTHE4&rft_id=info:doi/&rft_dat=%3Cproquest_pubme%3E1859371301%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1859371301&rft_id=info:pmid/11941090&rfr_iscdi=true