Role of nasopharyngeal bacterial flora in the evaluation of recurrent middle ear infections in children
To study the nasopharyngeal colonization in otitis-prone children before and after adenoidectomy. The study population consisted of 35 children between 11 months and 4 years of age, undergoing adenoidectomy and tube placement for recurrent acute otitis media. All these children were otitis prone (OP...
Gespeichert in:
| Veröffentlicht in: | Clinical microbiology and infection 1999-09, Vol.5 (9), p.530-534 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 534 |
|---|---|
| container_issue | 9 |
| container_start_page | 530 |
| container_title | Clinical microbiology and infection |
| container_volume | 5 |
| creator | Dhooge, Ingeborg Van Damme, Dominique Vaneechoutte, Mario Claeys, Geert Verschraegen, Gerda Van Cauwenberge, Paul |
| description | To study the nasopharyngeal colonization in otitis-prone children before and after adenoidectomy.
The study population consisted of 35 children between 11 months and 4 years of age, undergoing adenoidectomy and tube placement for recurrent acute otitis media. All these children were otitis prone (OP). During general anesthesia, bacteriologic samples were obtained from the nasopharynx and the middle ear fluid, if present. During the follow-up visit, a new nasopharyngeal culture was taken. The control population consisted of 35 children undergoing surgery for non-ear-nose-throat pathology. These children had no history of recurrent upper respiratory tract infections.
Colonization of the nasopharynx with potential pathogens (Streptococcus pneumoniae, Moraxella catarrhalis, Haemophilus influenzae) occurred significantly more in the OP children than in the non-OP children. Adenoidectomy resulted in a substantial decrease of potential middle ear pathogens in the nasopharynx and an increase of normal commensal flora. In about half of the patients, middle ear fluid was still present at the time of tube placement; in most instances, H. influenzae was cultured. Typing with arbitrarily primed PCR indicated substantial genetic diversity among the H. influenzae isolates studied.
Both cross-colonization (between sampling sites within the same patient and between siblings) and turnover appeared to be high. |
| doi_str_mv | 10.1111/j.1469-0691.1999.tb00430.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1859366204</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S1198743X14645389</els_id><sourcerecordid>45323262</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4560-ed00ec08261358c5220194ce0ee551f5aa5ce5e270a42d04522b8b02dbf7a1b3</originalsourceid><addsrcrecordid>eNqVkU9v1DAQxS0Eou3CV0BRxYFL0rEd5w8HpGpboNIiJNQDN8txJl2vvPZiJ6X99nW0EZU4gS8eyb83nnmPkHMKBU3nYlfQsmpzqFpa0LZti7EDKDkUDy_I6Z-nl6mmbZPXJf95Qs5i3AEA47x8TU4obQStoTwldz-8xcwPmVPRH7YqPLo7VDbrlB4xmFQN1geVGZeNW8zwXtlJjca7WRNQTyGgG7O96fvUB1VI5IB6JuIs0ltj-4S8Ia8GZSO-Xe4Vuf18fbv-mm--f7lZX25yXYoKcuwBUEPDKspFowVjQNtSIyAKQQehlNAokNWgStZDmYCu6YD13VAr2vEV-XBsewj-14RxlHsTNVqrHPopyrR3y6uKJbtW5PwvdOen4NJwkjFa8xaaKkEfj5AOPsaAgzwEs08uSQpyDkPu5Oy4nB2XcxhyCUM-JPG75Yep22P_LF3cT8D7BVBRKzsE5bSJzxyvKTQ8YZ-O2G9j8fE_JpDrzTfBITW4OjbA5Py9wSCjNug09iZFOMrem3_Z5wlkqrys</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>221739086</pqid></control><display><type>article</type><title>Role of nasopharyngeal bacterial flora in the evaluation of recurrent middle ear infections in children</title><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Access via Wiley Online Library</source><source>ProQuest Central UK/Ireland</source><source>Alma/SFX Local Collection</source><creator>Dhooge, Ingeborg ; Van Damme, Dominique ; Vaneechoutte, Mario ; Claeys, Geert ; Verschraegen, Gerda ; Van Cauwenberge, Paul</creator><creatorcontrib>Dhooge, Ingeborg ; Van Damme, Dominique ; Vaneechoutte, Mario ; Claeys, Geert ; Verschraegen, Gerda ; Van Cauwenberge, Paul</creatorcontrib><description>To study the nasopharyngeal colonization in otitis-prone children before and after adenoidectomy.
The study population consisted of 35 children between 11 months and 4 years of age, undergoing adenoidectomy and tube placement for recurrent acute otitis media. All these children were otitis prone (OP). During general anesthesia, bacteriologic samples were obtained from the nasopharynx and the middle ear fluid, if present. During the follow-up visit, a new nasopharyngeal culture was taken. The control population consisted of 35 children undergoing surgery for non-ear-nose-throat pathology. These children had no history of recurrent upper respiratory tract infections.
Colonization of the nasopharynx with potential pathogens (Streptococcus pneumoniae, Moraxella catarrhalis, Haemophilus influenzae) occurred significantly more in the OP children than in the non-OP children. Adenoidectomy resulted in a substantial decrease of potential middle ear pathogens in the nasopharynx and an increase of normal commensal flora. In about half of the patients, middle ear fluid was still present at the time of tube placement; in most instances, H. influenzae was cultured. Typing with arbitrarily primed PCR indicated substantial genetic diversity among the H. influenzae isolates studied.
Both cross-colonization (between sampling sites within the same patient and between siblings) and turnover appeared to be high.</description><identifier>ISSN: 1198-743X</identifier><identifier>EISSN: 1469-0691</identifier><identifier>DOI: 10.1111/j.1469-0691.1999.tb00430.x</identifier><identifier>PMID: 11851704</identifier><language>eng</language><publisher>Oxford, UK: Elsevier Ltd</publisher><subject>adenoidectomy ; Bacterial diseases ; bacteriology ; Biological and medical sciences ; Ent and stomatologic bacterial diseases ; Human bacterial diseases ; Infectious diseases ; Medical sciences ; nasopharynx ; Recurrent otitis media</subject><ispartof>Clinical microbiology and infection, 1999-09, Vol.5 (9), p.530-534</ispartof><rights>1999 European Society of Clinical Infectious Diseases</rights><rights>1999 European Society of Clinical Microbiology and Infectious Diseases</rights><rights>2000 INIST-CNRS</rights><rights>Copyright Decker Periodicals, Inc. Sep 1999</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4560-ed00ec08261358c5220194ce0ee551f5aa5ce5e270a42d04522b8b02dbf7a1b3</citedby><cites>FETCH-LOGICAL-c4560-ed00ec08261358c5220194ce0ee551f5aa5ce5e270a42d04522b8b02dbf7a1b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1469-0691.1999.tb00430.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/221739086?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,1417,27924,27925,45574,45575,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1371083$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11851704$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dhooge, Ingeborg</creatorcontrib><creatorcontrib>Van Damme, Dominique</creatorcontrib><creatorcontrib>Vaneechoutte, Mario</creatorcontrib><creatorcontrib>Claeys, Geert</creatorcontrib><creatorcontrib>Verschraegen, Gerda</creatorcontrib><creatorcontrib>Van Cauwenberge, Paul</creatorcontrib><title>Role of nasopharyngeal bacterial flora in the evaluation of recurrent middle ear infections in children</title><title>Clinical microbiology and infection</title><addtitle>Clin Microbiol Infect</addtitle><description>To study the nasopharyngeal colonization in otitis-prone children before and after adenoidectomy.
The study population consisted of 35 children between 11 months and 4 years of age, undergoing adenoidectomy and tube placement for recurrent acute otitis media. All these children were otitis prone (OP). During general anesthesia, bacteriologic samples were obtained from the nasopharynx and the middle ear fluid, if present. During the follow-up visit, a new nasopharyngeal culture was taken. The control population consisted of 35 children undergoing surgery for non-ear-nose-throat pathology. These children had no history of recurrent upper respiratory tract infections.
Colonization of the nasopharynx with potential pathogens (Streptococcus pneumoniae, Moraxella catarrhalis, Haemophilus influenzae) occurred significantly more in the OP children than in the non-OP children. Adenoidectomy resulted in a substantial decrease of potential middle ear pathogens in the nasopharynx and an increase of normal commensal flora. In about half of the patients, middle ear fluid was still present at the time of tube placement; in most instances, H. influenzae was cultured. Typing with arbitrarily primed PCR indicated substantial genetic diversity among the H. influenzae isolates studied.
Both cross-colonization (between sampling sites within the same patient and between siblings) and turnover appeared to be high.</description><subject>adenoidectomy</subject><subject>Bacterial diseases</subject><subject>bacteriology</subject><subject>Biological and medical sciences</subject><subject>Ent and stomatologic bacterial diseases</subject><subject>Human bacterial diseases</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>nasopharynx</subject><subject>Recurrent otitis media</subject><issn>1198-743X</issn><issn>1469-0691</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqVkU9v1DAQxS0Eou3CV0BRxYFL0rEd5w8HpGpboNIiJNQDN8txJl2vvPZiJ6X99nW0EZU4gS8eyb83nnmPkHMKBU3nYlfQsmpzqFpa0LZti7EDKDkUDy_I6Z-nl6mmbZPXJf95Qs5i3AEA47x8TU4obQStoTwldz-8xcwPmVPRH7YqPLo7VDbrlB4xmFQN1geVGZeNW8zwXtlJjca7WRNQTyGgG7O96fvUB1VI5IB6JuIs0ltj-4S8Ia8GZSO-Xe4Vuf18fbv-mm--f7lZX25yXYoKcuwBUEPDKspFowVjQNtSIyAKQQehlNAokNWgStZDmYCu6YD13VAr2vEV-XBsewj-14RxlHsTNVqrHPopyrR3y6uKJbtW5PwvdOen4NJwkjFa8xaaKkEfj5AOPsaAgzwEs08uSQpyDkPu5Oy4nB2XcxhyCUM-JPG75Yep22P_LF3cT8D7BVBRKzsE5bSJzxyvKTQ8YZ-O2G9j8fE_JpDrzTfBITW4OjbA5Py9wSCjNug09iZFOMrem3_Z5wlkqrys</recordid><startdate>199909</startdate><enddate>199909</enddate><creator>Dhooge, Ingeborg</creator><creator>Van Damme, Dominique</creator><creator>Vaneechoutte, Mario</creator><creator>Claeys, Geert</creator><creator>Verschraegen, Gerda</creator><creator>Van Cauwenberge, Paul</creator><general>Elsevier Ltd</general><general>Blackwell Publishing Ltd</general><general>Blackwell</general><general>Elsevier Limited</general><scope>6I.</scope><scope>AAFTH</scope><scope>IQODW</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FQ</scope><scope>8FV</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M3G</scope><scope>M7N</scope><scope>M7P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>199909</creationdate><title>Role of nasopharyngeal bacterial flora in the evaluation of recurrent middle ear infections in children</title><author>Dhooge, Ingeborg ; Van Damme, Dominique ; Vaneechoutte, Mario ; Claeys, Geert ; Verschraegen, Gerda ; Van Cauwenberge, Paul</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4560-ed00ec08261358c5220194ce0ee551f5aa5ce5e270a42d04522b8b02dbf7a1b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>adenoidectomy</topic><topic>Bacterial diseases</topic><topic>bacteriology</topic><topic>Biological and medical sciences</topic><topic>Ent and stomatologic bacterial diseases</topic><topic>Human bacterial diseases</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>nasopharynx</topic><topic>Recurrent otitis media</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dhooge, Ingeborg</creatorcontrib><creatorcontrib>Van Damme, Dominique</creatorcontrib><creatorcontrib>Vaneechoutte, Mario</creatorcontrib><creatorcontrib>Claeys, Geert</creatorcontrib><creatorcontrib>Verschraegen, Gerda</creatorcontrib><creatorcontrib>Van Cauwenberge, Paul</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Pascal-Francis</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Canadian Business & Current Affairs Database</collection><collection>Canadian Business & Current Affairs Database (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>CBCA Reference & Current Events</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical microbiology and infection</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dhooge, Ingeborg</au><au>Van Damme, Dominique</au><au>Vaneechoutte, Mario</au><au>Claeys, Geert</au><au>Verschraegen, Gerda</au><au>Van Cauwenberge, Paul</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of nasopharyngeal bacterial flora in the evaluation of recurrent middle ear infections in children</atitle><jtitle>Clinical microbiology and infection</jtitle><addtitle>Clin Microbiol Infect</addtitle><date>1999-09</date><risdate>1999</risdate><volume>5</volume><issue>9</issue><spage>530</spage><epage>534</epage><pages>530-534</pages><issn>1198-743X</issn><eissn>1469-0691</eissn><abstract>To study the nasopharyngeal colonization in otitis-prone children before and after adenoidectomy.
The study population consisted of 35 children between 11 months and 4 years of age, undergoing adenoidectomy and tube placement for recurrent acute otitis media. All these children were otitis prone (OP). During general anesthesia, bacteriologic samples were obtained from the nasopharynx and the middle ear fluid, if present. During the follow-up visit, a new nasopharyngeal culture was taken. The control population consisted of 35 children undergoing surgery for non-ear-nose-throat pathology. These children had no history of recurrent upper respiratory tract infections.
Colonization of the nasopharynx with potential pathogens (Streptococcus pneumoniae, Moraxella catarrhalis, Haemophilus influenzae) occurred significantly more in the OP children than in the non-OP children. Adenoidectomy resulted in a substantial decrease of potential middle ear pathogens in the nasopharynx and an increase of normal commensal flora. In about half of the patients, middle ear fluid was still present at the time of tube placement; in most instances, H. influenzae was cultured. Typing with arbitrarily primed PCR indicated substantial genetic diversity among the H. influenzae isolates studied.
Both cross-colonization (between sampling sites within the same patient and between siblings) and turnover appeared to be high.</abstract><cop>Oxford, UK</cop><pub>Elsevier Ltd</pub><pmid>11851704</pmid><doi>10.1111/j.1469-0691.1999.tb00430.x</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1198-743X |
| ispartof | Clinical microbiology and infection, 1999-09, Vol.5 (9), p.530-534 |
| issn | 1198-743X 1469-0691 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1859366204 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Access via Wiley Online Library; ProQuest Central UK/Ireland; Alma/SFX Local Collection |
| subjects | adenoidectomy Bacterial diseases bacteriology Biological and medical sciences Ent and stomatologic bacterial diseases Human bacterial diseases Infectious diseases Medical sciences nasopharynx Recurrent otitis media |
| title | Role of nasopharyngeal bacterial flora in the evaluation of recurrent middle ear infections in children |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T19%3A17%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Role%20of%20nasopharyngeal%20bacterial%20flora%20in%20the%20evaluation%20of%20recurrent%20middle%20ear%20infections%20in%20children&rft.jtitle=Clinical%20microbiology%20and%20infection&rft.au=Dhooge,%20Ingeborg&rft.date=1999-09&rft.volume=5&rft.issue=9&rft.spage=530&rft.epage=534&rft.pages=530-534&rft.issn=1198-743X&rft.eissn=1469-0691&rft_id=info:doi/10.1111/j.1469-0691.1999.tb00430.x&rft_dat=%3Cproquest_cross%3E45323262%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=221739086&rft_id=info:pmid/11851704&rft_els_id=S1198743X14645389&rfr_iscdi=true |