Cure of undifferentiated small cell carcinoma of the urinary bladder with M-VAC chemotherapy

Small cell carcinoma (SCC) of the urinary bladder is a rare, aggressive malignancy with approximately 135 cases reported in the literature. Treatments have included chemotherapy, radical surgery, radiotherapy, and combinations of these. We present the apparent cure of a 73-year-old man who presented...

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Veröffentlicht in:Urologic oncology 2001-03, Vol.6 (2), p.53-55
Hauptverfasser: Nejat, Robert J., Purohit, Ravjeer, Goluboff, Erik T., Petrylak, Daniel, Rubin, Mark A., Benson, Mitchell C.
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container_title Urologic oncology
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creator Nejat, Robert J.
Purohit, Ravjeer
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Rubin, Mark A.
Benson, Mitchell C.
description Small cell carcinoma (SCC) of the urinary bladder is a rare, aggressive malignancy with approximately 135 cases reported in the literature. Treatments have included chemotherapy, radical surgery, radiotherapy, and combinations of these. We present the apparent cure of a 73-year-old man who presented with clinical stage T2 SCC of the urinary bladder. He was treated with three cycles of methotrexate, vinblastine, Adriamycin (doxorubicin), and cisplatin (M-VAC) chemotherapy. Subsequent radical cystoprostatectomy revealed no pathologic evidence of tumor. The patient is alive and well with no evidence of recurrence 3 years post cystectomy. A brief review of the literature is also presented.
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subjects Bladder neoplasms
Carcinoma, small cell
Chemotherapy, adjuvant
title Cure of undifferentiated small cell carcinoma of the urinary bladder with M-VAC chemotherapy
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