A Kinetic Study on the Interaction between Tazobactam (A Penicillanic Acid Sulphone Derivative) and Active-Site Serine beta-Lactamases

The interaction between tazobactam and several chromosome- and plasmid-encoded (TEM, SHV, PSE types) class A and C beta-lactamases was studied by spectrophotometry. Tazobactam behaved as a competitive inhibitor or inactivator able to restore in several cases the efficiency of piperacillin as a partn...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of enzyme inhibition 1999-11, Vol.15 (1), p.1-10
Hauptverfasser:	Perilli, M, Franceschini, N, Bonfiglio, G, Segatore, B, Stefani, S, Nicoletti, G, Tavio Perez Md, Bianchi, C, Zollo, A, Amicosante, G
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!