Association of factor H of the alternative pathway of complement with agrin and complement receptor 3 in the Alzheimer's disease brain

Factor H, a regulatory protein of the alternative pathway of complement (APC), is present in amyloid- beta (A beta ) plaques in Alzheimer's disease (AD). A beta plaques also contain significant amounts of heparan sulfate proteoglycans (HSPGs), such as agrin, as well as numerous activated microg...

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Veröffentlicht in:Journal of neuroimmunology 2001-10, Vol.131 (1-2), p.135-146
Hauptverfasser: Strohmeyer, R, Ramirez, M, Cole, G J, Mueller, K, Rogers, J
Format: Artikel
Sprache:eng
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