Structural Diversity Based on Cyclopropane Scaffolds
A practical and efficient route for the stereoselective conversion of easily accessible homoallylic alcohols to diastereomerically pure cis- and trans-disubstituted and 1,2,3-trisubstituted cyclopropanes has been developed. The diversity of structures that can be prepared and the simplicity of the o...
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Veröffentlicht in: | Organic letters 2000-03, Vol.2 (5), p.601-603 |
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creator | Taylor, Richard E Schmitt, Michael J Yuan, Haiqing |
description | A practical and efficient route for the stereoselective conversion of easily accessible homoallylic alcohols to diastereomerically pure cis- and trans-disubstituted and 1,2,3-trisubstituted cyclopropanes has been developed. The diversity of structures that can be prepared and the simplicity of the overall sequence make this route ideal for extension to solid-phase synthesis techniques and ultimately combinatorial library generation. |
doi_str_mv | 10.1021/ol9913542 |
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title | Structural Diversity Based on Cyclopropane Scaffolds |
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