2'-Deoxycytidine kinase deficiency is a major determinant of 2-chloro-2'-deoxyadenosine resistance in lymphoid cell lines

2-Chloro-2'-deoxyadenosine, (CldAdo) resistance was developed in the W1L2 human B lymphoblastoid (resistance factor, 160) and L1210 murine leukemia (resistance factor, 605) cell lines by continuous exposure to CldAdo. Cross-resistance studies showed that while the variant lines generally retain...

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Veröffentlicht in:	Clinical cancer research 1995-04, Vol.1 (4), p.391-398
Hauptverfasser:	ORR, R. M, TALBOT, D. C, WYNNE AHERNE, G, FISHER, T. C, SERAFINOWSKI, P, HARRAP, K. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences General aspects Medical sciences Pharmacology. Drug treatments
Online-Zugang:	Volltext
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