Interactions between cutaneous afferent inputs to a withdrawal reflex in the decerebrated rabbit and their control by descending and segmental systems

Previous studies have suggested that activation of nociceptive afferents from the heel recruits a supraspinal mechanism, which is modulated by adrenergic descending inhibition, that augments withdrawal reflexes in medial gastrocnemius (MG) motoneurones. To test this idea, we have studied the tempora...

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Veröffentlicht in:	Neuroscience 2002-01, Vol.112 (3), p.555-571
Hauptverfasser:	Clarke, R.W, Eves, S, Harris, J, Peachey, J.E, Stuart, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenergic alpha-Agonists - pharmacology Adrenergic alpha-Antagonists - pharmacology adrenoceptors Afferent Pathways - physiopathology Animals Biological and medical sciences Decerebrate State - physiopathology Dexmedetomidine - pharmacology Dizocilpine Maleate - pharmacology Drug Synergism Efferent Pathways - physiopathology Electric Stimulation Excitatory Amino Acid Antagonists - pharmacology Fundamental and applied biological sciences. Psychology gate control Idazoxan - analogs & derivatives Idazoxan - pharmacology Imidazoles - pharmacology Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Muscle, Skeletal - physiopathology Naloxone - pharmacology Narcotic Antagonists - pharmacology Neurons, Afferent - physiology NMDA receptors nociception opioid receptors Rabbits Reflex - drug effects Reflex - physiology Skin - innervation Sural Nerve - physiopathology Tarsus, Animal - physiopathology Vertebrates: nervous system and sense organs wind-up
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