Markers of endothelial damage in patients with chronic kidney disease on hemodialysis

Patients with Stage 5 chronic kidney disease who are on hemodialysis (HD) remain in a chronic inflammatory state, characterized by the accumulation of uremic toxins that induce endothelial damage and cardiovascular disease (CVD). Our aim was to examine microvesicles (MVs), monocyte subpopulations, a...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2017-04, Vol.312 (4), p.F673-F681
Hauptverfasser:	Carmona, Andrés, Agüera, Maria L, Luna-Ruiz, Carlos, Buendía, Paula, Calleros, Laura, García-Jerez, Andrea, Rodríguez-Puyol, Manuel, Arias, Manuel, Arias-Guillen, Marta, de Arriba, Gabriel, Ballarin, Jose, Bernis, Carmen, Fernández, Elvira, García-Rebollo, Sagrario, Mancha, Javier, Del Peso, Gloria, Pérez, Estefanía, Poch, Esteban, Portolés, Jose M, Rodríguez-Puyol, Diego, Sánchez-Villanueva, Rafael, Sarro, Felipe, Torres, Armando, Martín-Malo, Alejandro, Aljama, Pedro, Ramírez, Rafael, Carracedo, Julia
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Angiopoietin-1 - blood Angiopoietin-2 - blood Biomarkers - blood Cardiovascular disease Case-Control Studies Cell-Derived Microparticles - metabolism Cell-Derived Microparticles - pathology Diabetes Diabetic Nephropathies - blood Diabetic Nephropathies - diagnosis Diabetic Nephropathies - mortality Diabetic Nephropathies - therapy Disease Progression Endothelial Cells - metabolism Endothelial Cells - pathology Female Flow cytometry Hemodialysis Humans Inflammation Mediators - blood Kaplan-Meier Estimate Kidney diseases Male Middle Aged Monocytes - metabolism Predictive Value of Tests Prevalence Renal Dialysis - adverse effects Renal Dialysis - mortality Renal Insufficiency, Chronic - blood Renal Insufficiency, Chronic - diagnosis Renal Insufficiency, Chronic - mortality Renal Insufficiency, Chronic - therapy Spain - epidemiology Time Factors Toxins Treatment Outcome
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