Clinical efficacy of oral alendronate in ankylosing spondylitis: a randomised placebo-controlled trial

A prospective, double blind, randomised, placebo controlled trial over 2 years was performed to test the efficacy of alendronate, an oral aminobisphosphonate, in improving symptoms and arrest disease progression in patients with mild to severe ankylosing spondylitis (AS). 180 patients with AS were r...

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Veröffentlicht in:	Clinical and experimental rheumatology 2017-05, Vol.35 (3), p.445-451
Hauptverfasser:	Coates, Lucy, Packham, Jonathan C, Creamer, Paul, Hailwood, Sarah, Bhalla, Ashley S, Chakravarty, Kuntal, Mulherin, Diamuid, Taylor, Gordon, Mattey, Derek L, Bhalla, Ashok K
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Adult Alendronate - administration & dosage Alendronate - adverse effects Biomarkers - blood Bone Density Conservation Agents - administration & dosage Bone Density Conservation Agents - adverse effects Disease Progression Double-Blind Method Female Humans Male Middle Aged Prospective Studies Severity of Illness Index Spondylitis, Ankylosing - blood Spondylitis, Ankylosing - diagnosis Spondylitis, Ankylosing - drug therapy Time Factors Treatment Outcome United Kingdom
Online-Zugang:	Volltext
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