Controlling the Helix Handedness of ααβ‐Peptide Foldamers through Sequence Shifting

Peptide foldamers containing both cis‐β‐aminocyclopentanecarboxylic acid and α‐amino acid residues combined in various sequence patterns (ααβ, αααβ, αβααβ, and ααβαααβ) were screened using CD and NMR spectroscopy for the tendency to form helices. ααβ‐Peptides were found to fold into an unprecedented...

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Veröffentlicht in:	Angewandte Chemie International Edition 2017-02, Vol.56 (8), p.2087-2091
Hauptverfasser:	Szefczyk, Monika, Węglarz‐Tomczak, Ewelina, Fortuna, Paulina, Krzysztoń, Agnieszka, Rudzińska‐Szostak, Ewa, Berlicki, Łukasz
Format:	Artikel
Sprache:	eng
Schlagworte:	foldamers helical propensity peptide structures peptides β-amino acids
Online-Zugang:	Volltext
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