Dopamine controls Parkinson's tremor by inhibiting the cerebellar thalamus

Parkinson's resting tremor is related to altered cerebral activity in the basal ganglia and the cerebello-thalamo-cortical circuit. Although Parkinson's disease is characterized by dopamine depletion in the basal ganglia, the dopaminergic basis of resting tremor remains unclear: dopaminerg...

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Veröffentlicht in:	Brain (London, England : 1878) England : 1878), 2017-03, Vol.140 (3), p.721-734
Hauptverfasser:	Dirkx, Michiel F, den Ouden, Hanneke E M, Aarts, Esther, Timmer, Monique H M, Bloem, Bastiaan R, Toni, Ivan, Helmich, Rick C
Format:	Artikel
Sprache:	eng
Schlagworte:	Bayes Theorem Brain Mapping Cerebellum - diagnostic imaging Cerebellum - drug effects Dopamine Agents - pharmacology Dopamine Agents - therapeutic use Electromyography Female Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Middle Aged Models, Neurological Neural Pathways - diagnostic imaging Neural Pathways - drug effects Nonlinear Dynamics Oxygen - blood Parkinson Disease - complications Parkinson Disease - diagnostic imaging Severity of Illness Index Thalamus - diagnostic imaging Thalamus - drug effects Tremor - diagnostic imaging Tremor - pathology Tremor - therapy
Online-Zugang:	Volltext
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